Biological Activity
Peptide 17 is a inhibitor of this YAP-TEAD protein-protein interaction which has potential usage in treatment of YAP-involved cancers with IC50 of 25nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 4.95 mL | 24.75 mL | 49.51 mL |
0.5 mM | 0.99 mL | 4.95 mL | 9.9 mL |
1 mM | 0.5 mL | 2.48 mL | 4.95 mL |
5 mM | 0.1 mL | 0.5 mL | 0.99 mL |
*The above data is based on the productmolecular weight 2019.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15858 |
---|---|
M. Wt | 2019.86 |
Formula | C93H144ClN23O21S2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | N/A |
Synonyms | YAP-TEAD Inhibitor 1 , Peptide-17, Peptide17 |
SMILES | C1(=O)N[[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]@H](CSSCC[[email protected]@H](C(=O)N[[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]](C(=O)N2[[email protected]]1CCC2)CCCC)CCCCN)CCCNC(=N)N)CC(C)C)NC(=O)[[email protected]@H](NC(=O)[[email protected]]1N(CCC1)C(=O)[[email protected]@H](NC(=O)C)C(C)C)Cc1cc(ccc1)Cl)C(=O)N[[email protected]](C(=O)N1[[email protected]](C(=O)N2[[email protected]](C(=O)N[[email protected]](C(=O)N)CCC(=O)O)CCC2)CCC1)CCCCN)Cc1ccccc1)CO)C |
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