Peptides

Items 2901-2950 of 3079

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  1. Dipeptide

    Beta-Asp-His is a dipeptide composed of aspartic acid and histidine that demonstrates the ability to form amino acid derivatives through complexation with zinc. This compound is of interest in biochemical research for its potential applications in enzyme regulation and metal-ion interactions. It may be utilized in studies focusing on zinc-dependent biological processes and the development of therapeutics targeting metalloproteins.
  2. Tripeptide

    H-Gly-Sar-Sar-OH is a tripeptide that exhibits oral bioactivity. It is efficiently transported through the peptide transporter 1 (PepT1) in Caco-2 cell models, suggesting its potential for enhanced absorption in therapeutic applications. This compound may be utilized in research focused on peptide transport mechanisms and material bioavailability.
  3. Dipeptide

    Fmoc-Ile-Thr(psi(Me,Me)pro)-OH is a dipeptide that incorporates a constrained proline analogue. This compound is designed to serve as a building block in the synthesis of peptides and proteins, offering enhanced stability and conformational rigidity. Its unique structure makes it valuable in research applications focused on peptide design, drug discovery, and the study of protein interactions.
  4. Dipeptide

    Fmoc-Lys(Boc)-Thr(psi(Me,Me)pro)-OH is a dipeptide that incorporates a lysine residue protected by a Boc group and a threonine analog with a modified proline structure. This compound is utilized in peptide synthesis and modifications for the exploration of peptide pharmacodynamics and structure-activity relationships. Its unique structural features enable researchers to study protein interactions and develop novel therapeutic agents.
  5. Dipeptide

    Fmoc-Phe-Thr(psi(Me,Me)pro)-OH is a dipeptide featuring a unique modified proline residue. This compound is designed to study peptide interactions and protein folding due to its structural variations. Its application is primarily in peptide synthesis and development, making it a valuable tool for researchers investigating peptide libraries and bioconjugation strategies.
  6. Dipeptide

    Fmoc-Trp(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide with a unique structure that incorporates a psi(Me,Me)pro residue. This compound is utilized in peptide synthesis and modification studies due to its ability to influence protein conformation and stability. Its unique features make it valuable for research in peptide-based therapeutics and structural biology.
  7. Dipeptide Et Ester

    Glp-Trp-OEt is a pyroglutamyl-tryptophan derivative functioning as a dipeptide ethyl ester. This compound is primarily utilized in biochemical research to study peptide synthesis and the role of dipeptides in biological systems. Its unique structure makes it valuable for exploring molecular interactions and activity in various biological assays.
  8. Polypeptide

    N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine is designed to interact with the PAICS protein, thereby inhibiting its activity. This compound effectively decreases the accumulation of SAICAR and SAICAr, making it a valuable tool in metabolic and biochemical research focused on purine biosynthesis. Its ability to modulate these pathways can aid in studies related to cancer metabolism and other disorders associated with nucleotide imbalances.
  9. Acidic Polypeptide

    Poly-L-aspartic acid is an acidic polypeptide known for its pH-dependent conformational changes. This compound is of significant interest in research focusing on pH-responsive structural transitions within biological systems. Its unique properties make it suitable for various applications in biochemistry and molecular biology.
  10. Chromogenic Peptide Substrate

    Tos-Gly-Pro-Arg-ANBA-IPA is a chromogenic peptide substrate that targets proteolytic enzymes. This compound is designed for use in luminescence assays, enabling the detection and quantification of enzyme activity. It serves as a valuable tool in biochemical research, facilitating studies in enzymology and related fields.
  11. Peptide Derivative

    Lys-Ala-βNA is a peptide derivative specifically designed as a substrate for Dipeptidyl peptidase III (DPP III). This compound plays a vital role in biochemical studies related to proteolysis and enzymatic activity. It is particularly useful for investigating the function and inhibition of DPP III in various biological systems.
  12. Polypeptide

    Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) is a cyclic polypeptide designed to target integrins, specifically facilitating cell adhesion and migration. Its structure incorporates an azido group, enabling conjugation chemistry for imaging or therapeutic applications. This compound is valuable in research focused on tumor targeting and angiogenesis, particularly in the synthesis of radiolabeled compounds such as [18F]FPyKYNE-c(RGDyK).
  13. Peptide Nucleic Acid Monomer

    Boc-PNA-T-OH is a thymine-containing peptide nucleic acid (PNA) monomer designed for solid-phase synthesis of PNA oligomers. This reagent facilitates the incorporation of thymine into PNA constructs, enabling researchers to explore gene recognition, regulation, and molecular diagnostics. Boc-PNA-T-OH is essential for applications in antisense technology, gene silencing, and the development of novel therapeutic agents.
  14. Peptide

    H-Arg-Ser-Arg-OH is a peptide that serves as a versatile building block for synthesizing larger peptide constructs. This sequence incorporates di-leucine and RSRR motifs, making it valuable in studies related to peptide design and functionality. Its applications extend to the exploration of peptide interactions and the development of therapeutic agents in various biological contexts.
  15. Peptide Nucleic Acid Monomer

    Fmoc-PNA-U-OH is a peptide nucleic acid monomer designed for the synthesis of peptide nucleic acids (PNAs). This compound exhibits specific binding affinity to adenine, enhanced resistance to enzymatic degradation, and robust hybridization capabilities. Fmoc-PNA-U-OH is valuable in various research applications, including gene diagnosis, molecular biology studies, and the development of antisense therapeutic strategies.
  16. Tripeptide

    ACV Tripeptide is a pivotal tripeptide that serves as the initial intermediate in the biosynthetic pathway for penicillin and cephalosporin classes of β-lactam antibiotics in bacteria and fungi. It is synthesized nonribosomally by the enzyme ACV synthetase (ACVS), encoded by the pchAB gene. This compound plays a crucial role in the production of β-lactam antibiotics, making it essential for research focused on antibiotic biosynthesis and the development of new antimicrobial agents.
  17. Peptide Nucleic Acid Monomer

    Fmoc-PNA-M(Boc)-OH is a peptide nucleic acid (PNA) monomer featuring Fmoc and Boc protecting groups. This compound is utilized in the synthesis of peptide nucleic acids, which serve as powerful tools in genetic research, diagnostics, and therapeutic applications. Its structural properties enable effective binding to complementary nucleic acid sequences, making it valuable for studies involving gene regulation, antisense strategies, and the development of nucleic acid-based therapeutics.
  18. Peptide Nucleic Acid Monomer

    Boc-PNA-C(Z)-OH is a peptide nucleic acid monomer featuring a protected cytosine. The amino group is safeguarded by a tert-butoxycarbonyl (Boc) group, while the cytosine is protected by a benzyloxycarbonyl (Z) group. This compound is essential for the synthesis of peptide nucleic acids, facilitating research in areas such as gene regulation, antisense oligonucleotide design, and studies on nucleic acid interactions.
  19. Fibrinopeptide B

    [Glu1]-Fibrinopeptide B is a bioactive fragment derived from the first 14 amino acid residues of fibrinopeptide B. It acts as a thrombin-derived proteolytic cleavage product of the fibrinogen B beta-chain, playing a significant role in stimulating human neutrophils, monocytes, and fibroblasts. This peptide is valuable in research applications related to inflammation, wound healing, and immunological responses.
  20. Peptide Nucleic Acid Monomer

    Fmoc-PNA-G(Bhoc)-OH is a guanine-containing peptide nucleic acid monomer featuring Bhoc and Fmoc protective groups on the nucleobase and backbone, respectively. This compound is essential for the synthesis of peptide nucleic acids, enabling the design of nucleic acid analogs with enhanced stability and versatility. Its unique properties facilitate research in areas such as gene expression regulation, antisense oligonucleotide development, and targeted therapeutic approaches.
  21. Insoluble Peptide

    4-(Hydroxymethyl)phenylacetic acid functions primarily as a key constituent in the synthesis of insoluble polypeptides. This compound can react with DEPBT and 4-acetylaniline to yield amide intermediates, facilitating various synthetic applications. Additionally, it is a metabolite arising from the microbial metabolism of flavonoids like quercetin. Notably, 4-(Hydroxymethyl)phenylacetic acid exhibits significant inhibitory effects on the oxidation of 6-mercaptopurine (6-MP), while demonstrating minimal impact on xanthine oxidation.
  22. Structural Unit of the Antitubercular Peptide

    (S)-3-Aminoazepan-2-one is a key structural unit of antitubercular peptides, functioning as the core scaffold for hexapeptide antibacterial agents. This compound exhibits significant biological activity against Mycobacterium tuberculosis, making it an important focus in tuberculosis research. Its role in the synthesis of novel antimicrobial agents contributes to the ongoing search for effective treatments against this infectious disease.
  23. α-helical Peptide

    Annulatin (3-O-Methylmyricetin) is an α-helical peptide that primarily induces histamine release from mast cells, which plays a critical role in allergic responses and immune regulation. Additionally, it exhibits low hemolytic activity, making it potentially useful for various research applications in immunology and cellular biology. Its unique properties may facilitate studies involving mast cell function and the modulation of immune responses.
  24. Tripeptide

    Copper tripeptide acetate (GHK-Cu acetate) targets various cellular pathways involved in skin regeneration. This tripeptide functions as a potent chemoattractant during wound healing, promoting the recruitment of inflammatory and endothelial cells. Research has demonstrated that Copper tripeptide acetate enhances the expression of messenger RNA for key structural components such as collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts, thereby supporting tissue repair and regeneration. Its role as a natural modulator makes it an important reagent for studies in dermatological research and regenerative medicine.
  25. Polystyrene Binding Peptide

    HWGMWSY is a polystyrene binding peptide that specifically interacts with polystyrene plastic surfaces. Its primary mechanism involves non-specific adhesion to various polymer substrates, facilitating studies of peptide-material interactions. This peptide is valuable in research applications focused on material science, biomaterials development, and peptide-based sensor technologies.
  26. Dipeptide

    H-Asn-Arg-OH is a dipeptide comprised of asparagine and arginine linked by a peptide bond. This compound is useful in the synthesis of polypeptides and can serve as a building block for developing biologically active peptides. Its applications extend to studies involving peptide interactions and function in various biological systems.
  27. Dipeptide

    Lysyllysine trihydrochloride is a dipeptide consisting of two linked L-lysine residues. This compound serves as an effective enzyme cleavage linker, facilitating the connection of bioactive peptides in various applications. Additionally, it plays a crucial role as a component in the development of complex antibacterial agents, contributing to research in peptide chemistry and antimicrobial efficacy.
  28. Synthetic Peptide

    Acetyl angiotensinogen (1-14), human is a synthetic peptide that represents the N-terminal acetylated form of human angiotensinogen (1-14). This compound serves as an important tool for studying the renin-angiotensin system and its role in hypertension and cardiovascular diseases. It is valuable in research applications involving peptide interactions and receptor signaling pathways relevant to blood pressure regulation and fluid homeostasis.
  29. Monocyclic Octapeptide

    Lyciumin C is a monocyclic octapeptide characterized by a unique C-N linkage between the nitrogen of tryptophan and the alpha carbon of glycine. This compound exhibits significant biological activity that supports its application in various pharmacological studies. Research indicates its potential roles in cell signaling and biological modulation, making it a valuable tool for investigations in peptide chemistry and therapeutic development.
  30. QP5

    Amelogenin-derived Peptide

    QP5 is an amelogenin-derived peptide that targets hydroxyapatite and demineralized tooth enamel surfaces. It transiently stabilizes amorphous calcium phosphate (ACP), regulates hydroxyapatite crystallization, and promotes remineralization of carious lesions. In rat caries models, QP5 has demonstrated significant efficacy in enhancing remineralization, making it valuable for research in oral diseases such as dental caries.
  31. Peptide

    hCT(18-32) is a peptide derived from human calcitonin (hCT), targeting the calcitonin receptor. This peptide exhibits significant biological activity by influencing calcium homeostasis and bone metabolism. hCT(18-32) is frequently utilized in research focused on osteoporosis, bone density regulation, and related metabolic disorders.
  32. Pentapeptide

    Cyclo(RGDfK(Mal)) is a cyclized pentapeptide that targets integrins, enhancing cell adhesion and infiltration of human pluripotent stem cells. This compound facilitates the development of 3D stem cell cultures, promoting effective expansion and maintenance of stem cell populations for research applications in regenerative medicine and tissue engineering.
  33. Dipeptide

    Lysyllysine (L-Lysyl-L-lysine) is a dipeptide formed by the linkage of two L-lysine amino acids. This compound serves as an effective enzyme cleavage linker for conjugating bioactive peptides, and it plays a role in the synthesis of more complex antibacterial agents. Its structural properties make it valuable in peptide chemistry and antimicrobial research applications.
  34. Synthetic Peptide Analogue

    IRI-514 is a synthetic peptide analogue of Thymopentin, functioning primarily in the modulation of neuroendocrine and behavioral responses to stress. This compound has been studied for its potential applications in understanding stress-related disorders and their effects on the neuroendocrine system. Researchers utilize IRI-514 to explore its effects on stress resilience and related physiological responses.
  35. Tripeptide

    Nle-Arg-Phe-NH2 acetate is a tripeptide compound that functions as a bioactive modulator in various biochemical pathways. This compound exhibits significant biological activity, including the potential to influence cell signaling and interaction. Nle-Arg-Phe-NH2 acetate is primarily utilized in research focusing on peptide synthesis, receptor studies, and investigations into the modulation of physiological responses.
  36. Natural Product

    Cycloleonuripeptide A is a natural product derived from motherwort, exhibiting a unique mechanism as a peptide compound. It has demonstrated potential anti-inflammatory and neuroprotective activities, making it a valuable candidate for research in pain management and neurodegenerative diseases. This compound is of interest for studies exploring the therapeutic benefits of natural products in pharmacological applications.
  37. Cyclic Peptide

    Pseudostellarin E is a cyclic peptide characterized by a proline-rich structure, derived from the roots of Pseudostellaria heterophylla. This compound can be synthesized through the overexpression of its precursor gene prePhPE in the leaves of Nicotiana benthamiana. Pseudostellarin E is of interest for its potential biological activities and applications in research focusing on cyclic peptides and their therapeutic implications.
  38. Peptide

    Cionin is a disulfotyrosyl hybrid peptide derived from cholecystokinin and gastrin. It primarily targets cholecystokinin receptors, mediating various physiological functions such as gastric motility and enzyme secretion. This compound is utilized in research applications examining gastrointestinal physiology and the endocrine system. Its unique structure allows for the exploration of receptor interactions and signaling pathways in peptide studies.
  39. peptide

    (β-Asp28)-Exenatide is a peptide derivative produced through the degradation of exenatide, resulting from the formation and cleavage of asparagine. This compound serves as a valuable tool for studying the stability and metabolism of exenatide in various biological settings. Its implications in pharmacological research enhance the understanding of peptide therapeutics and their potential modifications.
  40. Methionine Dipeptide

    H-Met-Met-OH, also known as L-Methionyl-L-methionine, is a dipeptide comprised of two methionine residues. This compound exhibits potential health benefits, particularly in nutritional studies and dietary applications. It is orally bioactive, making it suitable for research involving amino acid metabolism, protein synthesis, and supplementation effects in various animal models.
  41. PSM Peptide

    PSMα2 is a potent phenol-soluble modulin peptide that targets mouse neutrophils. It is known to induce a significant influx of leukocytes, making it valuable for studies on immune response mechanisms and inflammation. PSMα2 serves as a useful tool in research applications focused on elucidating neutrophil behaviors and their roles in various disease states.
  42. Dipeptide

    Prolylvaline (Pro-Val) is a dipeptide composed of proline and valine. This compound exhibits specific binding properties with fluorescein isothiocyanate (FITC) and demonstrates unique imprinting effects in Tetrahymena, leading to negative imprinting outcomes. Prolylvaline can be utilized in research to differentiate proline dipeptides with varying partner amino acids, thus providing insights into the structural and functional relationships of dipeptides based on amino acid positioning.
  43. Peptide

    Cyclo(Gly-Tyr) is a cyclic dipeptide that serves as a biochemical modulator due to its unique conformational stability. It exhibits key biological activities, potentially influencing neurotransmitter systems and cellular signaling pathways. This compound is valuable for research applications in peptide chemistry, neurobiology, and drug development, aiding in the exploration of peptide-based therapeutics and their physiological roles.
  44. Complementary Peptide

    SmBiT Tag is an 11 amino acid complementary peptide (VTGYRLFEEIL) that exhibits low affinity for LgBiT. This peptide is designed to facilitate bioluminescence assays and is instrumental in various protein-protein interaction studies. Its unique properties enable the precise measurement of molecular interactions in live cells, making it a valuable tool for researchers in the field of cellular signaling and protein technology.
  45. Anti-aging Peptide

    Palmitoyl tripeptide-5 diTFA is a bioactive peptide known for its anti-aging properties, primarily acting on skin regeneration and cellular repair. This compound promotes collagen synthesis and enhances skin elasticity, making it a valuable ingredient in cosmetic formulations aimed at reducing the appearance of fine lines and wrinkles. Its application extends to various skincare products designed to improve overall skin texture and resilience.
  46. Dipeptide

    L-Tryptophanylglycine (Trp-Gly) is a dipeptide that functions as an inhibitor of Ceronapril uptake in Caco-2 cells, exhibiting a Ki value of 7.19 mM. This compound can be utilized in studies of intestinal absorption and transport mechanisms, contributing valuable insights into drug bioavailability and the effects of dipeptides on cellular uptake processes.
  47. Osteoblast-Targeting-Peptide

    SDSSD is an osteoblast-targeting peptide that specifically binds to osteoblasts via periostin interactions. This peptide can be utilized to modify nanomaterials for in-depth studies of osteoblast-induced bone diseases, facilitating research into mechanisms of bone regeneration and pathology. Its selective targeting capabilities make it an essential tool for exploring osteoblast biology and developing potential therapeutic strategies.
  48. Cysteine-containing Polypeptide

    Ac-RFAAKAA-COOH is a cysteine-containing polypeptide characterized by its reactive lysine residue, making it a valuable substrate for covalent modification and chemical reactivity assays. This compound forms stable covalent adducts with isothiocyanates, which facilitates peptide depletion studies over time. Ac-RFAAKAA-COOH serves as a model peptide in direct peptide reactivity assays and is assessed using fluorescamine-based free amine assays. Its applications extend to research related to allergic contact dermatitis and skin sensitization mechanisms.
  49. N-Glycan

    Sialylglyco peptide is a sialylated glycopeptide that specifically targets N-Glycans. It exhibits key biological activity by participating in cell recognition processes and modulating cellular interactions. This compound is valuable in research applications focused on glycan recognition, cell signaling, and the study of glycoprotein-related diseases.
  50. PORK1 Agonist

    REF1 peptide is a potent PORK1 agonist with an EC50 of 0.028 nM in tomato. By binding to the extracellular domain of PORK1, REF1 peptide triggers receptor autophosphorylation, leading to the activation of downstream MPK3/MPK6 signaling pathways involved in defense and regeneration. This compound promotes callus formation and, with prolonged exposure, inhibits shoot regeneration, while enhancing regeneration and transformation efficiency in both recalcitrant dicotyledonous and monocotyledonous crops.

Items 2901-2950 of 3079

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