Catalog No.
Product Name
Application
Product Information
Citations
-
Cyclic Oligopeptide
Cyclosporin E, a cyclic oligopeptide originally isolated from fungi such as Trichoderma polysporum, exhibits properties relevant to the study of the Cyclosporin family. This compound is particularly valuable for investigating the structure-activity relationships and molecular dynamics of cyclosporins. Its unique structural attributes make Cyclosporin E an essential reagent in medicinal chemistry and biophysical research. -
Structural Unit of the Antitubercular Peptide
(S)-3-Aminoazepan-2-one is a key structural unit of antitubercular peptides, functioning as the core scaffold for hexapeptide antibacterial agents. This compound exhibits significant biological activity against Mycobacterium tuberculosis, making it an important focus in tuberculosis research. Its role in the synthesis of novel antimicrobial agents contributes to the ongoing search for effective treatments against this infectious disease. -
α-helical Peptide
Annulatin (3-O-Methylmyricetin) is an α-helical peptide that primarily induces histamine release from mast cells, which plays a critical role in allergic responses and immune regulation. Additionally, it exhibits low hemolytic activity, making it potentially useful for various research applications in immunology and cellular biology. Its unique properties may facilitate studies involving mast cell function and the modulation of immune responses. -
Tripeptide
Copper tripeptide acetate (GHK-Cu acetate) targets various cellular pathways involved in skin regeneration. This tripeptide functions as a potent chemoattractant during wound healing, promoting the recruitment of inflammatory and endothelial cells. Research has demonstrated that Copper tripeptide acetate enhances the expression of messenger RNA for key structural components such as collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts, thereby supporting tissue repair and regeneration. Its role as a natural modulator makes it an important reagent for studies in dermatological research and regenerative medicine. -
Polystyrene Binding Peptide
HWGMWSY is a polystyrene binding peptide that specifically interacts with polystyrene plastic surfaces. Its primary mechanism involves non-specific adhesion to various polymer substrates, facilitating studies of peptide-material interactions. This peptide is valuable in research applications focused on material science, biomaterials development, and peptide-based sensor technologies. -
Dipeptide
H-Asn-Arg-OH is a dipeptide comprised of asparagine and arginine linked by a peptide bond. This compound is useful in the synthesis of polypeptides and can serve as a building block for developing biologically active peptides. Its applications extend to studies involving peptide interactions and function in various biological systems. -
Dipeptide
Lysyllysine trihydrochloride is a dipeptide consisting of two linked L-lysine residues. This compound serves as an effective enzyme cleavage linker, facilitating the connection of bioactive peptides in various applications. Additionally, it plays a crucial role as a component in the development of complex antibacterial agents, contributing to research in peptide chemistry and antimicrobial efficacy. -
EphA4 Antagonist
KYL peptide is an EphA4 antagonist that selectively inhibits the EphA4 receptor, demonstrating an IC50 of 4.22 μM and a Kd of 1.3 μM. By binding to the ligand-binding domain of EphA4, KYL peptide effectively mitigates Aβ-induced synaptic dysfunction and enhances synaptic plasticity in models of Alzheimer's disease. Additionally, this peptide may facilitate nerve regeneration following injury and has potential applications in modulating immune responses. -
Syk
Syk Kinase Peptide Substrate is a specific peptide substrate designed for Syk kinase activity assays. This substrate enables researchers to study the phosphorylation activity of Syk kinase, which plays a critical role in immune response and signaling pathways. It is useful for applications involving signal transduction research and the investigation of Syk-related diseases. -
Synthetic Natriuretic/Vasorelaxing Peptide
Vasonatrin Peptide (VNP) is a synthetic chimera that combines the properties of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). It exhibits vasorelaxing effects, including enhanced venodilation typical of CNP and natriuretic activity associated with ANP, along with unique arterial vasodilating effects. VNP has been shown to protect against ischemia-reperfusion injury in diabetic models by modulating ER stress through the cGMP-PKG signaling pathway, making it a valuable tool for cardiovascular research. -
Synthetic Peptide
BPDEtide is a synthetic peptide designed as a selective substrate for cyclic guanosine monophosphate-dependent protein kinase (cGK) and cyclic adenosine monophosphate-dependent protein kinase (cAK). It demonstrates apparent Km values of 68 μM for cGK and 320 μM for cAK, highlighting its specificity for cGK activity measurement. This compound is valuable for studying cGK signaling pathways and assessing kinase activity in various biological research applications. -
G Substrate Peptide
G-Subtide is a G-substrate peptide that specifically targets Purkinje cells within the cerebellum. It serves as a preferred phosphorylation substrate for recombinant PfPKG2 protein, demonstrating limited activity outside of background levels. This reagent is useful for studying signaling pathways involving protein kinases and understanding cerebellar function at a molecular level. -
Syntenin Peptide Inhibitor
KSL 128114 is a potent peptide inhibitor of syntenin, targeting the PDZ1 domain with nanomolar affinity. This compound exhibits stability in human plasma and mouse hepatic microsomes, making it suitable for in vitro and in vivo studies. KSL 128114 demonstrates selective inhibition of syntenin, providing valuable insights into cellular signaling pathways and potential therapeutic applications in disorders associated with syntenin dysregulation. -
Cell Adhesion Peptide
H-Tyr-Ile-Gly-Ser-Arg-NH2 is a cell adhesion peptide that plays a crucial role in mediating cell adhesion and receptor interactions. This hexapeptide, derived from laminin, enhances epithelial cell adhesion properties, making it a valuable tool for studies in tissue engineering, cell migration, and regenerative medicine. Its ability to promote cell attachment and function makes it an important reagent for researchers investigating cellular behaviors in various biological contexts. -
Wound Healing Peptide
Tiger17 is a wound healing peptide that promotes tissue repair through the regulation of TGF-β1 secretion. It activates the Smad signaling pathway, specifically enhancing the phosphorylation of Smad2 and Smad3, which are crucial for cellular processes involved in wound healing. This peptide is valuable for research focused on tissue regeneration and therapeutic strategies for improving wound recovery. -
LSKL Control Peptide
SLLK is a control peptide for the LSKL sequence, serving as an essential tool in studies investigating Thrombospondin-1 (TSP1) inhibition. This peptide facilitates the evaluation of TSP1-related biological pathways and interactions, aiding in the understanding of angiogenesis and tissue repair processes. Its application is crucial in various research settings, including wound healing, cancer biology, and vascular biology. -
Pentapeptide
H-ILE-ARG-VAL-VAL-MET-OH is a pentapeptide that promotes cell adhesion through its specific domain. This sequence is known to interact with the thrombospondin-1 (TS1) receptor, facilitating various biological processes. Applications of H-ILE-ARG-VAL-VAL-MET-OH include studies on cell signaling, tissue engineering, and investigating the role of extracellular matrix components in cellular dynamics. -
Control Peptide
L-Seryl-L-leucyl-L-leucyl-L-lysine (SLLK) is a control peptide used in research applications to validate experimental results involving LSKL. This peptide serves as a reference to distinguish specific biological activity when investigating peptide interactions and effects. SLLK is essential for studies focusing on peptide functionality, binding assays, and exploring cellular responses in various biological contexts. -
ACTH Peptide
Acetyl-ACTH (2-24) is a peptide fragment derived from proopiomelanocortin (POMC) that targets the adrenocorticotropic hormone (ACTH) pathway. This peptide exhibits potent biological activity as an agonist at the melanocortin-1 (MC-1) receptor, influencing various physiological processes related to stress response and pigmentation. It is applicable in studies investigating the role of ACTH in hormonal regulation, obesity, and metabolic disorders, making it a valuable tool in endocrine research. -
ACTH Peptide
Acetyl-ACTH (3-24) is a synthetic peptide derived from proopiomelanocortin (POMC), specifically acting on the adrenocorticotrophic hormone (ACTH) pathway. This fragment plays a pivotal role as an agonist at the melanocortin-1 receptor (MC-1), influencing various physiological processes. Acetyl-ACTH (3-24) is utilized in research applications exploring stress response, skin pigmentation, and metabolic regulation. It serves as a valuable tool for studies related to the biological actions of melanocortin peptides. -
Coactivator-derived Mimic
SRC2-2 peptide is a coactivator-derived mimic that targets the androgen receptor (AR) ligand. It plays a vital role in modulating AR activity, making it a valuable tool for investigating mechanisms of prostate cancer progression and treatment. This peptide is suitable for studies focused on AR signaling pathways and the development of AR-targeted therapies. -
Atrial Natriuretic Peptide
Atriopeptin I (rat, mouse) is an atrial natriuretic peptide that primarily targets the regulation of cardiovascular homeostasis. It is known to stimulate testosterone production, exhibiting a half-maximum stimulation concentration of 38 nM. This reagent is valuable for research applications related to endocrine regulation and cardiovascular function, providing insights into physiological responses and potential therapeutic targets. -
ACTH Peptide
Acetyl-ACTH (4-24) is a fragment of proopiomelanocortin (POMC) that acts primarily on the melanocortin-1 receptor (MC-1). This peptide exhibits biological activities associated with the modulation of pigmentation and adrenal function. It is suitable for research applications focusing on stress response, melanogenesis, and the physiological effects of POMC-derived peptides in human, bovine, and rat models. -
Bioactive Peptide
SRC-1 NR box peptide is a bioactive peptide derived from a 14-amino acid fragment of the steroid receptor cofactor SRC-1 NR II. This peptide plays a crucial role in modulating the activity of estrogen receptor ligands and is valuable for investigating the regulatory mechanisms involved in estrogen signaling. Its applications extend to studies focused on hormone receptor interactions and related cellular processes. -
Synthetic Peptide
Acetyl angiotensinogen (1-14), human is a synthetic peptide that represents the N-terminal acetylated form of human angiotensinogen (1-14). This compound serves as an important tool for studying the renin-angiotensin system and its role in hypertension and cardiovascular diseases. It is valuable in research applications involving peptide interactions and receptor signaling pathways relevant to blood pressure regulation and fluid homeostasis. -
Monocyclic Octapeptide
Lyciumin C is a monocyclic octapeptide characterized by a unique C-N linkage between the nitrogen of tryptophan and the alpha carbon of glycine. This compound exhibits significant biological activity that supports its application in various pharmacological studies. Research indicates its potential roles in cell signaling and biological modulation, making it a valuable tool for investigations in peptide chemistry and therapeutic development. -
Amelogenin-derived Peptide
QP5 is an amelogenin-derived peptide that targets hydroxyapatite and demineralized tooth enamel surfaces. It transiently stabilizes amorphous calcium phosphate (ACP), regulates hydroxyapatite crystallization, and promotes remineralization of carious lesions. In rat caries models, QP5 has demonstrated significant efficacy in enhancing remineralization, making it valuable for research in oral diseases such as dental caries. -
Peptide
hCT(18-32) is a peptide derived from human calcitonin (hCT), targeting the calcitonin receptor. This peptide exhibits significant biological activity by influencing calcium homeostasis and bone metabolism. hCT(18-32) is frequently utilized in research focused on osteoporosis, bone density regulation, and related metabolic disorders. -
Pentapeptide
Cyclo(RGDfK(Mal)) is a cyclized pentapeptide that targets integrins, enhancing cell adhesion and infiltration of human pluripotent stem cells. This compound facilitates the development of 3D stem cell cultures, promoting effective expansion and maintenance of stem cell populations for research applications in regenerative medicine and tissue engineering. -
Dipeptide
Lysyllysine (L-Lysyl-L-lysine) is a dipeptide formed by the linkage of two L-lysine amino acids. This compound serves as an effective enzyme cleavage linker for conjugating bioactive peptides, and it plays a role in the synthesis of more complex antibacterial agents. Its structural properties make it valuable in peptide chemistry and antimicrobial research applications. -
Synthetic Peptide Analogue
IRI-514 is a synthetic peptide analogue of Thymopentin, functioning primarily in the modulation of neuroendocrine and behavioral responses to stress. This compound has been studied for its potential applications in understanding stress-related disorders and their effects on the neuroendocrine system. Researchers utilize IRI-514 to explore its effects on stress resilience and related physiological responses. -
Tripeptide
Nle-Arg-Phe-NH2 acetate is a tripeptide compound that functions as a bioactive modulator in various biochemical pathways. This compound exhibits significant biological activity, including the potential to influence cell signaling and interaction. Nle-Arg-Phe-NH2 acetate is primarily utilized in research focusing on peptide synthesis, receptor studies, and investigations into the modulation of physiological responses. -
Natural Product
Cycloleonuripeptide A is a natural product derived from motherwort, exhibiting a unique mechanism as a peptide compound. It has demonstrated potential anti-inflammatory and neuroprotective activities, making it a valuable candidate for research in pain management and neurodegenerative diseases. This compound is of interest for studies exploring the therapeutic benefits of natural products in pharmacological applications. -
Cyclic Peptide
Pseudostellarin E is a cyclic peptide characterized by a proline-rich structure, derived from the roots of Pseudostellaria heterophylla. This compound can be synthesized through the overexpression of its precursor gene prePhPE in the leaves of Nicotiana benthamiana. Pseudostellarin E is of interest for its potential biological activities and applications in research focusing on cyclic peptides and their therapeutic implications. -
Peptide
Cionin is a disulfotyrosyl hybrid peptide derived from cholecystokinin and gastrin. It primarily targets cholecystokinin receptors, mediating various physiological functions such as gastric motility and enzyme secretion. This compound is utilized in research applications examining gastrointestinal physiology and the endocrine system. Its unique structure allows for the exploration of receptor interactions and signaling pathways in peptide studies. -
peptide
(β-Asp28)-Exenatide is a peptide derivative produced through the degradation of exenatide, resulting from the formation and cleavage of asparagine. This compound serves as a valuable tool for studying the stability and metabolism of exenatide in various biological settings. Its implications in pharmacological research enhance the understanding of peptide therapeutics and their potential modifications. -
Acidic Polypeptide
Poly-L-aspartic acid is an acidic polypeptide known for its pH-dependent conformational changes. This compound is of significant interest in research focusing on pH-responsive structural transitions within biological systems. Its unique properties make it suitable for various applications in biochemistry and molecular biology. -
Chromogenic Peptide Substrate
Tos-Gly-Pro-Arg-ANBA-IPA is a chromogenic peptide substrate that targets proteolytic enzymes. This compound is designed for use in luminescence assays, enabling the detection and quantification of enzyme activity. It serves as a valuable tool in biochemical research, facilitating studies in enzymology and related fields. -
Peptide Derivative
Lys-Ala-βNA is a peptide derivative specifically designed as a substrate for Dipeptidyl peptidase III (DPP III). This compound plays a vital role in biochemical studies related to proteolysis and enzymatic activity. It is particularly useful for investigating the function and inhibition of DPP III in various biological systems. -
dipeptide
H-Gly-Arg-OH is a dipeptide composed of glycine and arginine. This compound serves as a substrate for various enzymes and plays a crucial role in cellular signaling pathways. H-Gly-Arg-OH is utilized in research applications focused on peptide synthesis, proteomics, and the study of protein interactions, contributing to the understanding of biological processes and potential therapeutic targets. -
TFLLR-NH2 Negative Control Peptide
RLLFT-NH2 is a reversed peptide sequence designed as a negative control for TFLLR-NH2. This compound serves as a valuable tool for researchers studying peptide functionalities and interactions, providing a baseline for comparison in experimental assays. Its application is crucial in validating results and ensuring specificity in peptide-related studies, enhancing the reliability of experimental data. -
Peptide-Linked Tracer
Bevonescein (ALM-488) is a fluorescein-conjugated peptide that serves as a targeted tracer for the delivery of fluorescent moieties to nerve tissues following intravenous administration. It specifically binds to nerve-associated connective tissue, enabling real-time fluorescence imaging of peripheral nerves in living organisms as well as human ex vivo nerve samples. Suitable for visualizing both intact and degenerated nerves, Bevonescein exhibits an excitation/emission peak at 480/530 nm, making it valuable for neurobiological research and applications in nerve injury studies. -
Natriuretic Peptide
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled targets the natriuretic peptide system and is crucial for regulating fluid homeostasis and blood pressure. This biotin-labeled peptide facilitates the study of cardiovascular physiology and pathophysiology. It holds potential for applications in cardiovascular disease research and the development of therapeutic interventions. -
Peptide
Biotin-myelin basic protein (94-102) is a peptide fragment that plays a critical role in myelination within the nervous system. It facilitates the adhesion of cytosolic surfaces in multilayered compact myelin and functions as a membrane actin-binding protein, potentially linking extracellular signaling to the cytoskeleton in oligodendrocytes. This peptide is valuable for research applications focused on myelination processes and oligodendrocyte function. -
Fluorescent Peptide Substrate
Suc-Leu-Tyr-AMC is a fluorescent peptide substrate designed specifically for µ-calpain and m-calpain enzymes. It is characterized by an excitation wavelength of 360 nm and an emission wavelength of 460 nm, making it suitable for fluorescence-based assays. This reagent serves as a vital tool in studying calpain activity and related biological processes. Its application in research can aid in the understanding of proteolytic cleavage and its implications in various physiological and pathological conditions. -
Fluorescent peptide substrate
H-GLU-AMC-OH is a fluorescent peptide substrate specifically designed for the assessment of aminopeptidase A enzyme activity. This compound enables sensitive quantification and observation of enzyme kinetics in various biological samples. Its application is beneficial in studies involving peptide metabolism and enzyme regulation, providing valuable insights into aminotransferase functions. -
Dansyl-Labeled Peptide
Dansyl-Gly-Cys-Val-Leu-Ser is a dansyl-labeled peptide primarily recognized for its ability to facilitate fluorescence studies of peptide interactions and conformational dynamics. This compound serves as a valuable tool in biochemical and biophysical research, enabling researchers to investigate protein folding, binding affinities, and proteolytic activity. Its fluorescent properties make it an ideal candidate for studies involving cellular uptake and localization. -
Bioactive Peptide
Z-Gly-Gly-Arg-AFC is a bioactive peptide that serves as a substrate for plasminogen activators. This compound possesses fluorescent properties, making it a valuable tool for studying enzyme activity in various biological assays. Applications include the investigation of plasminogen activation pathways and screening for potential therapeutic agents targeting these pathways. -
Peptide Chromogenic Substrate
N-(p-Tosyl)-GPR-pNA acetate is a chromogenic substrate specifically designed for the assessment of synthetic peptides, particularly Hirunorm IV and Hirunorm V. This reagent is utilized to determine the dissociation constants (KI) of these reversible inhibitors of thrombin activity. Through the modulation of peptide concentration, precise evaluation of dissociation constants can be achieved, with values measured at 0.134 nM for Hirunorm IV and 0.245 nM for Hirunorm V, enhancing research in the field of coagulation and fibrinolysis studies. -
Peptide
Bz-RGFFL-4MβNA is a fluorogenic peptide substrate with the sequence Bz-Arg-Gly-Phe-Phe-Leu-4MβNA. This compound is designed for use in enzymatic assays and can facilitate the study of protease activity. Its unique fluorescent properties allow for sensitive detection and quantification in various biological research applications, providing valuable insights into cellular processes and enzyme kinetics.
