Catalog No.
Product Name
Application
Product Information
Citations
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Dipeptide
Arginylaspartic acid acetate is a dipeptide that contains arginine and aspartic acid. It is recognized for its role in various biological processes, including modulation of cell signaling and enhancement of peptide transport. This reagent serves as a valuable tool in research applications focused on peptide biology, drug design, and cellular interactions. -
Tumor-targeted peptide
A7RC is a tumor-targeted peptide that incorporates Cysteine at the C-terminal of the A7R sequence (ATWLPPR). It serves as a ligand for the NRP-1 receptor, playing a crucial role in the regulation of intracellular signaling pathways associated with tumor vascularization and growth. A7RC is primarily utilized in research focusing on targeted cancer therapies and the modulation of tumor microenvironments. -
Dipeptide
H-His-Arg-OH is a dipeptide featuring guanidine groups that serves as a potent dissociating agent. It effectively reduces the critical micelle concentration, facilitating the formation of stable nano emulsions. This reagent is valuable in research applications involving nanoparticle stabilization and formulation development. -
Phosphine-functionalized Flag Peptide
Phos-FLAG is a phosphorylated FLAG peptide that facilitates Staudinger-like linkage reactions with azide-modified cell surface glycans and glycoproteins. This reactive probe allows for the quantitative detection of azide-labeled glycans in various biological samples, including isolated cell and organ lysates. Phos-FLAG is particularly valuable for studying glycan modifications and their roles in cellular processes and disease states. Its application in click chemistry further enhances its utility in the field of glycobiology. -
dipeptide
H-Gly-Arg-OH is a dipeptide composed of glycine and arginine. This compound serves as a substrate for various enzymes and plays a crucial role in cellular signaling pathways. H-Gly-Arg-OH is utilized in research applications focused on peptide synthesis, proteomics, and the study of protein interactions, contributing to the understanding of biological processes and potential therapeutic targets. -
TFLLR-NH2 Negative Control Peptide
RLLFT-NH2 is a reversed peptide sequence designed as a negative control for TFLLR-NH2. This compound serves as a valuable tool for researchers studying peptide functionalities and interactions, providing a baseline for comparison in experimental assays. Its application is crucial in validating results and ensuring specificity in peptide-related studies, enhancing the reliability of experimental data. -
Peptide-Linked Tracer
Bevonescein (ALM-488) is a fluorescein-conjugated peptide that serves as a targeted tracer for the delivery of fluorescent moieties to nerve tissues following intravenous administration. It specifically binds to nerve-associated connective tissue, enabling real-time fluorescence imaging of peripheral nerves in living organisms as well as human ex vivo nerve samples. Suitable for visualizing both intact and degenerated nerves, Bevonescein exhibits an excitation/emission peak at 480/530 nm, making it valuable for neurobiological research and applications in nerve injury studies. -
Natriuretic Peptide
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled targets the natriuretic peptide system and is crucial for regulating fluid homeostasis and blood pressure. This biotin-labeled peptide facilitates the study of cardiovascular physiology and pathophysiology. It holds potential for applications in cardiovascular disease research and the development of therapeutic interventions. -
Peptide
Biotin-myelin basic protein (94-102) is a peptide fragment that plays a critical role in myelination within the nervous system. It facilitates the adhesion of cytosolic surfaces in multilayered compact myelin and functions as a membrane actin-binding protein, potentially linking extracellular signaling to the cytoskeleton in oligodendrocytes. This peptide is valuable for research applications focused on myelination processes and oligodendrocyte function. -
Fluorescent Peptide Substrate
Suc-Leu-Tyr-AMC is a fluorescent peptide substrate designed specifically for µ-calpain and m-calpain enzymes. It is characterized by an excitation wavelength of 360 nm and an emission wavelength of 460 nm, making it suitable for fluorescence-based assays. This reagent serves as a vital tool in studying calpain activity and related biological processes. Its application in research can aid in the understanding of proteolytic cleavage and its implications in various physiological and pathological conditions. -
Fluorescent peptide substrate
H-GLU-AMC-OH is a fluorescent peptide substrate specifically designed for the assessment of aminopeptidase A enzyme activity. This compound enables sensitive quantification and observation of enzyme kinetics in various biological samples. Its application is beneficial in studies involving peptide metabolism and enzyme regulation, providing valuable insights into aminotransferase functions. -
Dansyl-Labeled Peptide
Dansyl-Gly-Cys-Val-Leu-Ser is a dansyl-labeled peptide primarily recognized for its ability to facilitate fluorescence studies of peptide interactions and conformational dynamics. This compound serves as a valuable tool in biochemical and biophysical research, enabling researchers to investigate protein folding, binding affinities, and proteolytic activity. Its fluorescent properties make it an ideal candidate for studies involving cellular uptake and localization. -
Bioactive Peptide
Z-Gly-Gly-Arg-AFC is a bioactive peptide that serves as a substrate for plasminogen activators. This compound possesses fluorescent properties, making it a valuable tool for studying enzyme activity in various biological assays. Applications include the investigation of plasminogen activation pathways and screening for potential therapeutic agents targeting these pathways. -
Peptide Chromogenic Substrate
N-(p-Tosyl)-GPR-pNA acetate is a chromogenic substrate specifically designed for the assessment of synthetic peptides, particularly Hirunorm IV and Hirunorm V. This reagent is utilized to determine the dissociation constants (KI) of these reversible inhibitors of thrombin activity. Through the modulation of peptide concentration, precise evaluation of dissociation constants can be achieved, with values measured at 0.134 nM for Hirunorm IV and 0.245 nM for Hirunorm V, enhancing research in the field of coagulation and fibrinolysis studies. -
Peptide
Bz-RGFFL-4MβNA is a fluorogenic peptide substrate with the sequence Bz-Arg-Gly-Phe-Phe-Leu-4MβNA. This compound is designed for use in enzymatic assays and can facilitate the study of protease activity. Its unique fluorescent properties allow for sensitive detection and quantification in various biological research applications, providing valuable insights into cellular processes and enzyme kinetics. -
Cell Penetrating Peptide
CPP12 is a small amphipathic cyclic cell-penetrating peptide that facilitates cellular uptake by binding to plasma membrane phospholipids and entering cells through endocytosis, followed by effective endosomal escape. This peptide is valuable for the intracellular delivery of therapeutic agents and chemical probes, making it a useful tool in various biological research applications and therapeutic development. -
Cell Penetrating Peptide
CPP9 is a cyclic cell penetrating peptide that facilitates the translocation of therapeutic agents across cell membranes. Its amphipathic properties enable CPP9 to interact with plasma membrane phospholipids, allowing for cellular entry via endocytosis and subsequent endosomal release. This peptide is effective for the intracellular delivery of various compounds, making it a valuable tool in chemical research and drug development applications. -
Fluorogenic Peptide Substrate
Dabcyl-GLRTQSFS-EDANS is a fluorogenic peptide substrate designed to assess the enzymatic activity of Hepatitis A Virus 3C proteinase. This substrate provides a means to study proteolytic processes and the dynamics of viral infections. Its fluorescent characteristics enable the sensitive detection of enzymatic cleavage, making it a valuable tool in virology research and drug development studies. -
Bioactive Peptide
H-D-Val-Leu-Lys-AFC is a bioactive peptide that serves as a fluorescent substrate for plasmin, exhibiting an absorption/emission peak at 380/500 nm. As a member of the serine protease family, plasmin is essential for fibrinolysis, facilitating the dissolution of fibrin in blood clots. Additionally, plasmin plays significant roles in various physiological and pathological processes, including wound healing, liver repair, and the maintenance of liver homeostasis, making this peptide useful in research applications focused on these biological pathways. -
Fluorogenic Peptide
Cbz-Lys-Lys-PABA-AMC diTFA is a fluorogenic peptide designed to function as a substrate for proteases. It exhibits high specificity for certain enzymes, enabling the detection and quantification of proteolytic activity in biological samples. This compound is valuable in studies requiring the measurement of enzyme kinetics, protease activity, and related metabolic processes. -
Dabsyl-labeled Peptide.
Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans is a Dabsyl-labeled peptide designed as a fluorophore substrate for studying peptidase activity. It serves as a specific probe for evaluating the enzymatic activity of the LasA protease from Pseudomonas aeruginosa. This reagent is valuable in research focused on protease function and substrate specificity, facilitating insights into microbial proteolytic mechanisms. -
Peptide Substrate
Dnp-RPLALWRS is a fluorescent peptide substrate specifically tailored for human matrilysin (MMP-7). Upon enzymatic cleavage at the alanine-leucine bond, the release of the Dnp group enhances fluorescence by alleviating quenching, allowing for real-time quantitative assessment of MMP-7 activity through increased tryptophan emission. This substrate serves as a sensitive and effective tool for conducting kinetic studies and screening for enzyme inhibitors. -
Bioactive Peptide
5-FAM-Pro-Leu-OH is a bioactive peptide designed for use as a fluorescent reference standard for matrix metalloproteinases (MMPs). This compound exhibits key biological activity related to proteolytic enzyme inhibition and provides a valuable tool for analyzing MMP activity in various research applications. It is particularly useful in studies focusing on tissue remodeling, cancer metastasis, and wound healing. -
Peptide Bond Forming Agent
HOAT (1-Hydroxy-7-azabenzotriazole) serves as a peptide bond forming agent, facilitating the formation of amide bonds in peptide synthesis. It is particularly useful in peptide fragment polycondensation, where it enhances efficiency while reducing the racemization of products. Due to its non-mutagenic properties, HOAT is considered safe for various applications in peptide chemistry. -
Macrocyclic Peptide Antibiotic
Capreomycin is a macrocyclic peptide antibiotic that primarily targets mycobacterial ribosomes. It inhibits phenylalanine synthesis during the translation process, making it effective in combating multidrug-resistant tuberculosis. This compound is valuable for research focused on tuberculosis treatment and the mechanisms of antibiotic resistance in mycobacteria. -
Dipeptide
H-His-His-OH is a dipeptide that serves as a metal ion chelator, specifically interacting with Ruthenium (II). This compound demonstrates the ability to inhibit the hydrolysis of metal ions at physiological pH 7.4, making it a valuable tool in biochemical research. Its chelating properties may be utilized in studies related to metal ion metabolism and the development of metal-based therapeutics. -
Scrambled Control Peptide
YRLGRW is a scrambled control peptide designed to validate experimental results involving the WYRGRL peptide sequence. By serving as a non-bioactive counterpart, YRLGRW aids in determining the specificity and biological activity of WYRGRL in various research applications. This control peptide is essential for studies focusing on peptide interactions, signaling pathways, and cellular responses in biochemical assays. -
Neural Adhesion/Differentiation Signal Peptide
IKVAVC is a modified peptide of IKVAV, featuring a cysteine residue at the C-terminus that facilitates covalent conjugation to various molecular platforms. It functions as a neural adhesion and differentiation signaling peptide, preserving the biological activities of IKVAV. IKVAVC inhibits fibroblast migration and activation, downregulates the TGF-β1 signaling pathway and endoplasmic reticulum stress, and supports nerve repair. Additionally, it promotes a phenotypic shift in macrophages from the pro-inflammatory M1 state to the pro-reparative M2 state, thereby enhancing tissue regeneration processes. -
HER2-targeting Peptide
HER2-targeted peptide H10 is designed to specifically bind to the HER2 receptor, exhibiting a Kd value of 3.04 × 10^-8 M. This peptide effectively accumulates in HER2-positive tumor tissues in xenograft mouse models when conjugated with nanoparticles. It serves as a valuable tool for research into the mechanisms and treatment strategies related to HER2-positive breast cancer. -
Laminin-Mimetic Peptide
YIGSRC is a laminin-mimetic peptide that promotes endothelial cell adhesion and facilitates tube formation. This peptide includes a cysteine residue, enabling chemical modification to hydrogels through thiol-ene reactions. YIGSRC is valuable in enhancing in vitro vascularization studies, making it a critical tool for tissue engineering and regenerative medicine research. -
Membrane-Lytic Peptide
p5RHH is an acid-activated membrane-lytic peptide derived from melittin, designed to facilitate siRNA delivery. This peptide promotes the synchronous disassembly of nanocomplexes and induces endosomal lysis in response to acidic pH levels, effectively triggering the release of siRNA into the cytoplasm through macropinocytosis. p5RHH is valuable for research applications focusing on gene silencing and RNA interference strategies. -
Peptide
HW12 is a random peptide with an N-terminal cysteine, serving primarily as a control for GE11-conjugated mixed micelles targeting the epidermal growth factor receptor (EGFR). This peptide exhibits cytotoxic activity, inhibits cellular uptake, and suppresses tumor growth. HW12 is particularly relevant for research focused on pancreatic cancer, providing essential insights into therapeutic strategies and mechanisms of action related to EGFR-targeted treatments. -
VEGFR Ligand
Peptide HRH is a polypeptide that specifically targets vascular endothelial growth factor receptors (VEGFR). It effectively inhibits VEGF-stimulated endothelial cell proliferation, thereby disrupting angiogenesis. Additionally, Peptide HRH demonstrates efficacy in suppressing corneal neovascularization. This peptide is suitable for research applications focused on anti-angiogenesis and related studies. -
Dipeptide
Glu-Cys (glutamyl-cysteine) is a dipeptide formed from L-glutamic acid and L-cysteine, connected via a peptide bond. This compound plays a crucial role in protein synthesis and cellular antioxidant defense mechanisms. Glu-Cys has applications in biochemical research, particularly in studying redox biology and the regulation of glutathione metabolism. -
Dipeptide
Cyclo(leucylleucine) is a cyclic dipeptide that results from the cyclization of two leucine residues through peptide bond formation. This compound may be utilized in the synthesis of nanomaterials due to its unique structural properties. Its distinctive conformation and stability make it a valuable reagent for research in materials science and drug delivery applications. -
Fusogenic peptide
HA2 peptide is a potent pH-sensitive fusogenic peptide derived from hemagglutinin (HA), primarily targeting cellular membranes to facilitate fusion. This anionic peptide can be conjugated with cationic peptides to effectively condense siRNA, which is crucial for gene delivery applications. HA2 peptide is widely utilized in research focused on cancer therapeutics and the development of novel drug delivery systems. -
Cyclic Peptide
Argyrin G is a natural cyclic non-ribosomal peptide that exhibits significant antimicrobial activity. This compound has been shown to interact with bacterial cell membranes, disrupting their integrity and leading to antibacterial effects. Argyrin G is primarily utilized in the study of antimicrobial agents and has potential applications in drug discovery and development for treating infections. -
Cyclic Peptide
Argyrin H is a natural cyclic non-ribosomal peptide that targets various biological pathways. It exhibits potent antimicrobial activity and has been implicated in research regarding antibiotic resistance. Its unique structure and mechanism make it a valuable tool for studying peptide biology and developing new therapeutic agents. -
Cyclic Peptide
Argyrin E is a natural cyclic peptide that exhibits potent antimicrobial activity by targeting bacterial cell membrane integrity. It is derived from non-ribosomal synthesis, making it a valuable tool for investigating peptide-based antibacterial mechanisms. This compound is useful in research applications focused on antibiotic resistance and the development of new antimicrobial therapies. -
β-sheet Peptide Foldamer
β4-TAT is a β-sheet peptide foldamer designed to target and influence the aggregation of fused in sarcoma (FUS) proteins by interacting with their RNA recognition motifs (RRM). Composed of a β4 sequence derived from the FUS RRM domain and a TAT sequence that facilitates nuclear localization, β4-TAT effectively induces FUS aggregation within cells, resulting in apoptosis of cancer cells. This reagent is valuable for research into FUS-related pathologies and the mechanisms underlying cancer cell death. -
Tag peptide
Avi Tag is a versatile short peptide tag designed for applications in protein expression and biotin labeling. This tag facilitates the site-specific attachment of biotin, enabling robust detection and purification of proteins using avidin or streptavidin-based methods. Its utility extends to various research applications, including functional assays, immunology studies, and protein-protein interaction investigations, enhancing experimental techniques in molecular biology. -
Artificially Designed Peptide
Decapeptide DP1 is an artificially designed peptide composed of ten amino acids (DEHGTAVMLK) that acts as a ligand to mimic components of the natural Mn²⁺ antioxidant complex. This peptide is integral in constructing the potent radiation protection agent MDP (Mn²⁺-DP1-Pi complex), demonstrating key biological activity in mitigating oxidative stress. Decapeptide DP1 is applicable in research focusing on antioxidant mechanisms and protective strategies against radiation-induced damage. -
Neuropeptide
Frog 26RFa is a neuropeptide derived from frog brain tissue, known for its pro-oxygen activity. This compound plays a significant role in neurobiology by modulating signaling pathways involved in various physiological processes. Research applications include studies on neuropeptide signaling, respiratory mechanisms, and potential therapeutic explorations in neurodegenerative diseases. -
T Cell Modulatory Peptide
Lysyl-serine is a T cell modulatory peptide known for its immunomodulatory properties. This compound plays a crucial role in enhancing T cell responses, making it valuable for research in immunology and potential therapeutic applications in autoimmune diseases and cancer. Its ability to modulate immune cell activity positions Lysyl-serine as a significant tool for studies focusing on the interplay between the immune system and disease. -
Mastoparan Family Peptide
Mastoparan-V1 is a peptide from the Mastoparan family that targets mast cells. It demonstrates moderate mast cell degranulation activity, with an EC50 of 130.24 μM in RBL-2H3 cells. This compound is useful for investigating mechanisms of allergic reactions, particularly those triggered by wasp stings. -
Neurohormones
Short Neuropeptide F is an insect neurohormone that primarily targets neurohormonal pathways. It plays a crucial role in modulating locomotor activity and regulating circadian rhythms in insects. This peptide is valuable for research applications focused on neurobiology, entomology, and the study of circadian systems. -
Bone-targeting Peptide
(Asp-Ser-Ser)6, also known as DSS6, is a synthetic bone-targeting peptide specifically designed to enhance bone tissue affinity. This compound serves as a ligand for modifying apoptotic extracellular vesicles (ApoEVs), thereby improving their targeting efficiency and therapeutic effectiveness in osteoporosis treatment. (Asp-Ser-Ser)6 is useful for research aimed at understanding and developing strategies for osteoporosis management. -
Polypeptide
Pyr-Gly-Arg-pNA is a synthetic substrate specifically designed for the enzyme tryptase, commonly found in guinea pig and human lung tissues. This compound exhibits key biological activity by facilitating the study of tryptase enzymatic activity, thereby contributing to research in inflammation and allergic responses. Its application in biochemical assays aids in the understanding of tryptase's role in various physiological and pathological processes. -
MHC class II epitope antigen
M30 peptide is an MHC class II epitope antigen that plays a crucial role in initiating T cell responses. This peptide is particularly valuable in cancer nanovaccine research, facilitating the development of targeted immunotherapies. By enhancing antigen presentation, M30 peptide supports investigations into adaptive immune responses against tumors. -
Immunomodulating Peptide
Thymotrinan is a biologically active fragment of the thymus hormone thymopoietin, functioning as an immunomodulating peptide. This compound exhibits immunomodulatory activities akin to TP5, influencing both humoral and cellular immune responses. Thymotrinan is suitable for research focused on immunoregulation and therapeutic applications in immune-related disorders.
