Catalog No.
Product Name
Application
Product Information
Citations
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Peptide Chromogenic Substrate
N-(p-Tosyl)-GPR-pNA acetate is a chromogenic substrate specifically designed for the assessment of synthetic peptides, particularly Hirunorm IV and Hirunorm V. This reagent is utilized to determine the dissociation constants (KI) of these reversible inhibitors of thrombin activity. Through the modulation of peptide concentration, precise evaluation of dissociation constants can be achieved, with values measured at 0.134 nM for Hirunorm IV and 0.245 nM for Hirunorm V, enhancing research in the field of coagulation and fibrinolysis studies. -
Peptide
Bz-RGFFL-4MβNA is a fluorogenic peptide substrate with the sequence Bz-Arg-Gly-Phe-Phe-Leu-4MβNA. This compound is designed for use in enzymatic assays and can facilitate the study of protease activity. Its unique fluorescent properties allow for sensitive detection and quantification in various biological research applications, providing valuable insights into cellular processes and enzyme kinetics. -
Cell Penetrating Peptide
CPP12 is a small amphipathic cyclic cell-penetrating peptide that facilitates cellular uptake by binding to plasma membrane phospholipids and entering cells through endocytosis, followed by effective endosomal escape. This peptide is valuable for the intracellular delivery of therapeutic agents and chemical probes, making it a useful tool in various biological research applications and therapeutic development. -
Cell Penetrating Peptide
CPP9 is a cyclic cell penetrating peptide that facilitates the translocation of therapeutic agents across cell membranes. Its amphipathic properties enable CPP9 to interact with plasma membrane phospholipids, allowing for cellular entry via endocytosis and subsequent endosomal release. This peptide is effective for the intracellular delivery of various compounds, making it a valuable tool in chemical research and drug development applications. -
Fluorogenic Peptide Substrate
Dabcyl-GLRTQSFS-EDANS is a fluorogenic peptide substrate designed to assess the enzymatic activity of Hepatitis A Virus 3C proteinase. This substrate provides a means to study proteolytic processes and the dynamics of viral infections. Its fluorescent characteristics enable the sensitive detection of enzymatic cleavage, making it a valuable tool in virology research and drug development studies. -
Bioactive Peptide
H-D-Val-Leu-Lys-AFC is a bioactive peptide that serves as a fluorescent substrate for plasmin, exhibiting an absorption/emission peak at 380/500 nm. As a member of the serine protease family, plasmin is essential for fibrinolysis, facilitating the dissolution of fibrin in blood clots. Additionally, plasmin plays significant roles in various physiological and pathological processes, including wound healing, liver repair, and the maintenance of liver homeostasis, making this peptide useful in research applications focused on these biological pathways. -
Fluorogenic Peptide
Cbz-Lys-Lys-PABA-AMC diTFA is a fluorogenic peptide designed to function as a substrate for proteases. It exhibits high specificity for certain enzymes, enabling the detection and quantification of proteolytic activity in biological samples. This compound is valuable in studies requiring the measurement of enzyme kinetics, protease activity, and related metabolic processes. -
Dabsyl-labeled Peptide.
Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans is a Dabsyl-labeled peptide designed as a fluorophore substrate for studying peptidase activity. It serves as a specific probe for evaluating the enzymatic activity of the LasA protease from Pseudomonas aeruginosa. This reagent is valuable in research focused on protease function and substrate specificity, facilitating insights into microbial proteolytic mechanisms. -
Peptide Substrate
Dnp-RPLALWRS is a fluorescent peptide substrate specifically tailored for human matrilysin (MMP-7). Upon enzymatic cleavage at the alanine-leucine bond, the release of the Dnp group enhances fluorescence by alleviating quenching, allowing for real-time quantitative assessment of MMP-7 activity through increased tryptophan emission. This substrate serves as a sensitive and effective tool for conducting kinetic studies and screening for enzyme inhibitors. -
Bioactive Peptide
5-FAM-Pro-Leu-OH is a bioactive peptide designed for use as a fluorescent reference standard for matrix metalloproteinases (MMPs). This compound exhibits key biological activity related to proteolytic enzyme inhibition and provides a valuable tool for analyzing MMP activity in various research applications. It is particularly useful in studies focusing on tissue remodeling, cancer metastasis, and wound healing. -
Peptide Bond Forming Agent
HOAT (1-Hydroxy-7-azabenzotriazole) serves as a peptide bond forming agent, facilitating the formation of amide bonds in peptide synthesis. It is particularly useful in peptide fragment polycondensation, where it enhances efficiency while reducing the racemization of products. Due to its non-mutagenic properties, HOAT is considered safe for various applications in peptide chemistry. -
Macrocyclic Peptide Antibiotic
Capreomycin is a macrocyclic peptide antibiotic that primarily targets mycobacterial ribosomes. It inhibits phenylalanine synthesis during the translation process, making it effective in combating multidrug-resistant tuberculosis. This compound is valuable for research focused on tuberculosis treatment and the mechanisms of antibiotic resistance in mycobacteria. -
Dipeptide
H-His-His-OH is a dipeptide that serves as a metal ion chelator, specifically interacting with Ruthenium (II). This compound demonstrates the ability to inhibit the hydrolysis of metal ions at physiological pH 7.4, making it a valuable tool in biochemical research. Its chelating properties may be utilized in studies related to metal ion metabolism and the development of metal-based therapeutics. -
Scrambled Control Peptide
YRLGRW is a scrambled control peptide designed to validate experimental results involving the WYRGRL peptide sequence. By serving as a non-bioactive counterpart, YRLGRW aids in determining the specificity and biological activity of WYRGRL in various research applications. This control peptide is essential for studies focusing on peptide interactions, signaling pathways, and cellular responses in biochemical assays. -
Neural Adhesion/Differentiation Signal Peptide
IKVAVC is a modified peptide of IKVAV, featuring a cysteine residue at the C-terminus that facilitates covalent conjugation to various molecular platforms. It functions as a neural adhesion and differentiation signaling peptide, preserving the biological activities of IKVAV. IKVAVC inhibits fibroblast migration and activation, downregulates the TGF-β1 signaling pathway and endoplasmic reticulum stress, and supports nerve repair. Additionally, it promotes a phenotypic shift in macrophages from the pro-inflammatory M1 state to the pro-reparative M2 state, thereby enhancing tissue regeneration processes. -
HER2-targeting Peptide
HER2-targeted peptide H10 is designed to specifically bind to the HER2 receptor, exhibiting a Kd value of 3.04 × 10^-8 M. This peptide effectively accumulates in HER2-positive tumor tissues in xenograft mouse models when conjugated with nanoparticles. It serves as a valuable tool for research into the mechanisms and treatment strategies related to HER2-positive breast cancer. -
Laminin-Mimetic Peptide
YIGSRC is a laminin-mimetic peptide that promotes endothelial cell adhesion and facilitates tube formation. This peptide includes a cysteine residue, enabling chemical modification to hydrogels through thiol-ene reactions. YIGSRC is valuable in enhancing in vitro vascularization studies, making it a critical tool for tissue engineering and regenerative medicine research. -
Membrane-Lytic Peptide
p5RHH is an acid-activated membrane-lytic peptide derived from melittin, designed to facilitate siRNA delivery. This peptide promotes the synchronous disassembly of nanocomplexes and induces endosomal lysis in response to acidic pH levels, effectively triggering the release of siRNA into the cytoplasm through macropinocytosis. p5RHH is valuable for research applications focusing on gene silencing and RNA interference strategies. -
Peptide
HW12 is a random peptide with an N-terminal cysteine, serving primarily as a control for GE11-conjugated mixed micelles targeting the epidermal growth factor receptor (EGFR). This peptide exhibits cytotoxic activity, inhibits cellular uptake, and suppresses tumor growth. HW12 is particularly relevant for research focused on pancreatic cancer, providing essential insights into therapeutic strategies and mechanisms of action related to EGFR-targeted treatments. -
VEGFR Ligand
Peptide HRH is a polypeptide that specifically targets vascular endothelial growth factor receptors (VEGFR). It effectively inhibits VEGF-stimulated endothelial cell proliferation, thereby disrupting angiogenesis. Additionally, Peptide HRH demonstrates efficacy in suppressing corneal neovascularization. This peptide is suitable for research applications focused on anti-angiogenesis and related studies. -
Dipeptide
Glu-Cys (glutamyl-cysteine) is a dipeptide formed from L-glutamic acid and L-cysteine, connected via a peptide bond. This compound plays a crucial role in protein synthesis and cellular antioxidant defense mechanisms. Glu-Cys has applications in biochemical research, particularly in studying redox biology and the regulation of glutathione metabolism. -
Dipeptide
Cyclo(leucylleucine) is a cyclic dipeptide that results from the cyclization of two leucine residues through peptide bond formation. This compound may be utilized in the synthesis of nanomaterials due to its unique structural properties. Its distinctive conformation and stability make it a valuable reagent for research in materials science and drug delivery applications. -
Fusogenic peptide
HA2 peptide is a potent pH-sensitive fusogenic peptide derived from hemagglutinin (HA), primarily targeting cellular membranes to facilitate fusion. This anionic peptide can be conjugated with cationic peptides to effectively condense siRNA, which is crucial for gene delivery applications. HA2 peptide is widely utilized in research focused on cancer therapeutics and the development of novel drug delivery systems. -
Cyclic Peptide
Argyrin G is a natural cyclic non-ribosomal peptide that exhibits significant antimicrobial activity. This compound has been shown to interact with bacterial cell membranes, disrupting their integrity and leading to antibacterial effects. Argyrin G is primarily utilized in the study of antimicrobial agents and has potential applications in drug discovery and development for treating infections. -
Cyclic Peptide
Argyrin H is a natural cyclic non-ribosomal peptide that targets various biological pathways. It exhibits potent antimicrobial activity and has been implicated in research regarding antibiotic resistance. Its unique structure and mechanism make it a valuable tool for studying peptide biology and developing new therapeutic agents. -
Cyclic Peptide
Argyrin E is a natural cyclic peptide that exhibits potent antimicrobial activity by targeting bacterial cell membrane integrity. It is derived from non-ribosomal synthesis, making it a valuable tool for investigating peptide-based antibacterial mechanisms. This compound is useful in research applications focused on antibiotic resistance and the development of new antimicrobial therapies. -
Cyclic Pentapeptide
Plactin C is a cyclic pentapeptide that promotes the dissolution of fibrinolytic proteins through its physiological activity. This compound is utilized in research applications focusing on coagulation processes and the study of fibrinolysis. Its unique structure and mechanism may aid in understanding the regulation of thrombosis and related cardiovascular conditions. -
Oligopeptide
Gly-Glu-Gly is a tripeptide that serves as a key tool for studying protein structure and dynamics. This oligopeptide provides insights into the interactions and behavior of specific amino acid residues during the protein folding process. Its applications extend to various biochemical and molecular biology research scenarios, aiding in the understanding of peptide bonding and conformational stability. -
Cyclic Pentapeptide
Plactin D is a cyclic pentapeptide that serves as a physiologically active compound, known for its ability to promote the dissolution of fibrinolytic proteins. It exhibits significant biological activity in supporting fibrinolysis, making it valuable for research applications focused on coagulation processes and the study of thrombotic disorders. This compound may contribute to the understanding of fibrin regulation and potential therapeutic approaches in related conditions. -
Cyclic Pentapeptide
Plactin B is a cyclic pentapeptide that enhances the dissolution of fibrinolytic proteins. This compound exhibits significant biological activity, making it valuable for research applications focused on fibrinolysis and related processes. Its ability to influence protein dissolution positions it as a useful tool for investigating thrombotic disorders and promoting vascular health. -
Dipeptide
His-Pro hydrochloride is a dipeptide composed of histidine and proline. It is primarily utilized in biochemical research to study peptide interactions and biological activities. His-Pro hydrochloride may serve as a valuable tool for exploring the role of dipeptides in cellular processes and for investigating potential therapeutic applications. -
Linear Tetrapeptide
Padanamide A is a linear tetrapeptide that functions as an inhibitor of cysteine and methionine biosynthesis. This compound demonstrates significant biological activity by disrupting the production of these essential amino acids. Padanamide A is applicable in research focusing on metabolic processes and the regulation of amino acid synthesis. -
Dipeptide
N-Acetylglutaminylglutamine amide is a dipeptide that serves as a key player in the osmotic stress response in bacteria such as Rhizobium meliloti and Pseudomonas fluorescens. This compound is useful for studies on bacterial adaptation mechanisms to environmental stressors and can be applied in research focusing on microbial physiology and metabolism. Its role in osmoregulation makes it a valuable reagent for investigating dipeptide functions in various biological contexts. -
Cyclic Peptide
Mycoplanecin C is a cyclic peptide that exhibits potent antimicrobial activity. It functions by inhibiting bacterial cell wall synthesis, making it a valuable tool in the study of bacterial resistance mechanisms. This compound is primarily utilized in research applications focusing on antibiotic discovery and the exploration of novel therapeutic agents against resistant bacterial strains. -
Cys Dipeptide
Ac-Cys-NHMe is a cysteine dipeptide featuring a thiol group that plays a significant role in redox biology. This compound serves as an important tool for studying cysteine-related biochemical pathways and oxidative stress responses. Its biological activity makes it suitable for research applications exploring protein folding, enzyme function, and cellular signaling processes involving thiol chemistry. -
Dipeptide
Glycyl-L-valine is a dipeptide featuring glycine and L-valine as its constituent amino acids. This compound is known for its role in protein synthesis and peptide formation. It is employed in various biochemical research applications, including studies on peptide behavior, interactions, and their physiological impacts in biological systems. -
Peptide
H-Cys-Val-2-Nal-Met-OH is a peptidomimetic derivative that targets peptide sequences, facilitating the labeling of short peptide motifs. This compound exhibits key biological activity that supports research focused on peptide interactions and structure-function studies. Its application in various biochemical assays makes it a valuable tool for researchers investigating peptide-based phenomena. -
Epitope peptide
PRAME peptide (425-433) is an epitope peptide corresponding to amino acids 425-433 of the PRAME (preferentially expressed antigen) protein, a key target in melanoma research. This peptide effectively stimulates human PRAME-specific CD8+ T cells, making it valuable for investigating T cell responses and potential immunotherapeutic strategies in melanoma. Its application in research facilitates the understanding of PRAME's role in tumor immunology. -
Hair Cell Targeting-Peptide
Hair cell targeting-peptide A665 is a specific ligand for the prestin protein located on the surface of inner ear hair cells. This peptide can be effectively incorporated into nanocarriers and combined with cell-penetrating peptides to improve drug delivery across the blood-labyrinth barrier. Its unique binding properties make it a valuable tool for research focused on inner ear drug delivery and potential therapeutic interventions for hearing loss. -
TRP-1 Peptide Sequence
TRP-1 (106-130) is a peptide derived from tyrosinase-related protein 1, functioning as a specific target for T cell activation. This peptide sequence can effectively stimulate and enhance the activity of T cells that recognize the TRP-1 antigen, making it valuable for research in immunology and cancer therapy. It is particularly useful in studies focused on T cell responses and the development of cancer vaccines. -
Cyclic Pentapeptide
Plactin A is a cyclic pentapeptide that facilitates the dissolution of fibrinolytic proteins. This compound exhibits significant biological activity in promoting fibrinolysis, making it valuable for research on clot resolution and related pathways. Its mechanism of action can be utilized in studies focused on hemostasis and vascular health. -
Dipeptide
Thr-Leu is a dipeptide comprised of threonine and leucine. It can be hydrolyzed in the peritoneal cavity, yielding its constituent amino acids and enhancing the osmotic pressure of the dialysate. Thr-Leu is valuable for kinetic studies related to amino acid-based peritoneal dialysis fluids, contributing to an improved understanding of their efficacy in clinical applications. -
Cyclic Peptide
Mycoplanecin D is a cyclic peptide known for its potent antimicrobial activity. It exhibits effectiveness against a range of bacterial strains, making it a valuable compound for pharmaceutical research focused on antibiotic development. Its unique structure and mechanism of action provide insights into peptide-based therapeutics and the exploration of novel antibacterial agents. -
Cyclodepsipeptide
Sporidesmolide III is a cyclodepsipeptide derived from the fungus Penicillium chartarum. It exhibits notable biological activity by inhibiting the protein phosphatase 1 (PP1) and has shown potential anti-cancer properties. This compound is utilized in research applications focusing on cellular signaling pathways and therapeutic development for various malignancies. -
Peptide
Bursin triacetate is a peptide that primarily targets B-cell phenotypic differentiation. This compound enhances the differentiation of B precursor cells across species, including mammals and birds. Bursin triacetate has been observed to elevate cyclic guanosine monophosphate (cGMP) levels in the human B-cell line Daudi, highlighting its potential for research in immunology and cell signaling pathways. -
Amphiphilic Peptides
H-Arg-Phe-OH is an amphiphilic peptide that facilitates native-like protein aggregation. It effectively promotes the aggregation of neutral model proteins, such as yeast alcohol dehydrogenase (ADH). This reagent is valuable for investigating protein folding, aggregation processes, and the study of related biochemical pathways. -
Tumor-homing Peptide
GX1 is a tumor-homing peptide with the amino acid sequence CGNSNPKSC, designed to specifically target the vascular endothelial cells associated with gastric cancer. This peptide serves as a valuable imaging probe, enabling the visualization of angiogenesis in gastric cancer tissues. Its specific targeting capability makes it a useful tool for cancer research applications focused on tumor vasculature. -
RPE-binding Peptide
MH42 is a peptide that specifically binds to retinal pigment epithelial (RPE) cells. This high-affinity binding allows for the potential study of RPE cell function and pathology, making it a valuable tool for researchers investigating retinal diseases and cellular processes in ophthalmology. Its applications include exploring cell signaling pathways and developing targeted delivery systems for therapeutics. -
Neuropeptide
Antho-RPamide II hydrochloride is a bioactive neuropeptide that targets neuronal signaling pathways. Isolated from the sea anemone Anthopleura elegantissima, this compound has been demonstrated to inhibit spontaneous rhythmic contractions in tentacle longitudinal muscle fibers of the organism. Antho-RPamide II hydrochloride offers valuable applications in research related to neurobiology and muscle physiology. -
Premature Ovarian Failure Inducer
Murine ZP3 peptide (330-342) specifically targets the zona pellucida 3 polypeptide and contains the amino acid sequence NSSSSQFQIHGPR. This peptide induces autoimmune premature ovarian failure (POF), making it a valuable tool for investigating the mechanisms underlying this condition. Research applications include studying ovarian function and the autoimmune aspects of reproductive health.
