Catalog No.
Product Name
Application
Product Information
Citations
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NG2 Targeting Peptide
NG2 Binding Peptide is a selective ligand that targets the NG2 proteoglycan, identified through phage display technology. This peptide engages specifically with NG2 binding sites, facilitating precise targeting of tumor-associated angiogenesis in both in vitro and in vivo models. Demonstrating notable homing capabilities in wild-type tumor-bearing mice, it has no localization in NG2 knockout models, underscoring its specificity. Due to the restricted expression of NG2 in certain tissues, NG2 Binding Peptide is suitable for applications in tumor-targeted therapy, drug delivery, and molecular imaging diagnostics. -
Neuropeptide
Tnrnflrfamide is a neuropeptide that primarily targets the muscular receptors in crustaceans, specifically modulating the lobster's abdominal stretch receptors and their analogous exoskeletal muscle systems. This compound enhances motor performance by increasing the amplitude of excitatory postsynaptic potentials and promoting the development of nerve-evoked tension. Tnrnflrfamide is valuable for research into neuromuscular function and the physiological mechanisms of motor control in invertebrates. -
Self-assembling Peptide
RAD-SKP peptide is a self-assembling peptide that facilitates the synthesis of nanofiber hydrogels in conjunction with decellularized cartilage matrix (DCM). This peptide plays a crucial role in cartilage repair research by providing a biomimetic extracellular environment. Its unique properties enable the development of advanced scaffolds for tissue engineering applications, promoting cellular behavior and enhancing regenerative potential in cartilage tissue. -
Leucokinin Peptide
Leukokinin 1 is a peptide from the leucokinin family that functions primarily through the activation of specific G-protein-coupled receptors (GPCRs). This compound is crucial for modulating various physiological processes within the central nervous system (CNS) of molluscs. Its unique biological activity makes it a valuable tool for research investigating neurological diseases and the underlying mechanisms of CNS function. -
Peptide
gp100 (17-25) is an immunogenic peptide targeting HLA-A3. It is capable of generating tumor-specific T lymphocytes, making it a valuable tool in melanoma research. This peptide can facilitate studies on immune response and therapeutic strategies against melanoma by activating anti-tumor T cell responses. -
KRAS WT Peptide
KRAS WT Peptide is the unmodified peptide derived from the Kirsten rat sarcoma virus (KRAS) gene, serving as a reference for wild-type sequences. This peptide is critical for evaluating the specificity and safety of KRAS-targeted immunotherapies. It is an essential tool for researchers studying KRAS-related oncogenesis and therapeutic applications in various cancer types. -
Cyclic Dipeptide
Cyclo(Ala-Gln) is a cyclic dipeptide characterized as a 2,5-diketopiperazine (DKP). This compound demonstrates potential biological activity as a modulator of various cellular processes, making it relevant for studies in peptide biology and drug development. Its unique structure may facilitate exploration into the mechanisms of peptide interactions and offers applications in therapeutic research and biochemical assays. -
Neuroexcitatory Tetrapeptide
Achatin I is a neuroexcitatory tetrapeptide that acts on voltage-gated ion channels to induce a voltage-dependent inward current. This compound displays significant excitatory effects on the giant neurons of Achatina, specifically the PON, TAN, and V-RCDN cells. Achatin I is primarily utilized in research on neurophysiology and synaptic transmission, offering insights into neuronal excitability and cellular signaling mechanisms. -
Chimeric Peptide
GGGGSGGGGS is a chimeric peptide that effectively interacts with small intestinal submucosa (SIS) membranes. This compound demonstrates significant binding affinity and can be utilized in research focused on infectious and inflammatory conditions. Its unique properties make it a valuable tool for studies investigating gastrointestinal pathologies and associated therapies. -
MAGE-A4 Peptide Segment
MAGE-A4 (286-294) is a peptide segment derived from the MAGE-A4 protein, specifically encompassing the amino acids 286 to 294. This peptide exhibits a high binding affinity for HLA-A*02, with an affinity of 560.08 nM and an IC50 of 8.52 nM. MAGE-A4 (286-294) is detectable in various malignancies, including esophageal cancer, lung squamous cell carcinoma, and bladder cancer, making it a valuable target in cancer immunotherapy. It is suitable for generating CAR-T cells and advancing CAR-T cell therapy applications in oncological research. -
Peptide
Cys-flag peptide (CDYKDDDDK) is a FLAG tag peptide modified to include cysteine, facilitating targeted interactions for protein purification and detection. This peptide is instrumental in various research applications, particularly in the study of neurological diseases, including Alzheimer's disease. Its specific binding properties enable efficient and effective tracking of FLAG-tagged proteins in experimental settings. -
Hexameric Peptide
Py-Aib6-Py is a hexameric peptide consisting of alpha-aminoisobutyric acid residues. This peptide can adopt an alpha helical conformation, making it a valuable tool for studies on peptide folding and structure-function relationships. It is suitable for applications in biophysical research and peptide design investigations. -
tau Peptide
AADvac 1 is an active tau peptide vaccine targeting tau pathology in Alzheimer's disease research. This vaccine consists of the regulatory peptide 294KDNIKHVPGGGS305, which promotes tau oligomerization, conjugated to Aplysia hemocyanin (KLH) and formulated with aluminum hydroxide as an adjuvant. AADvac 1 has potential applications in studying immune responses to tau aggregates, contributing to the understanding of Alzheimer's disease mechanisms and therapeutic strategies. -
Neuropeptide
Metamorphosin A is a neuropeptide derived from Anthopleura elegantissima that serves as a potent inducer of metamorphosis in Hydractinia echinata. This peptide plays a crucial role in the regulation of developmental processes and can be utilized in research exploring neuropeptide signaling pathways and developmental biology. Its unique biological activity makes it a valuable tool for studies involving metamorphic stages in marine invertebrates. -
Peptide Synthesis
H-Gly-D-Tyr-OH is a key reagent utilized in solid-phase peptide synthesis. It serves as an important building block for constructing peptides with diverse biological activities. This compound is essential for researchers aiming to synthesize peptides for studies in drug development, biochemistry, and molecular biology. -
Mitochondrial-Derived Peptide
SHLP-4 is a mitochondrial-derived peptide that plays a role in cellular signaling and metabolism. This biologically active microprotein, encoded by the 16S ribosomal RNA (MT-RNR2) gene, has been shown to enhance the proliferation of mouse NIT-1 insulinoma cells. SHLP-4 is suitable for research applications focused on diabetes and cardiovascular diseases, providing insights into mitochondrial function and its influence on metabolic health. -
CD9-binding Peptide
CD9-binding peptide is designed to selectively inhibit the interaction between EWI-2 and CD9. This peptide demonstrates significant anti-migratory and anti-invasive properties against various cancer cell lines. It serves as a valuable tool for investigating the role of CD9 in cancer research and potential therapeutic applications in oncology. -
Dipeptide
DB02307 is a dipeptide composed of two alpha-amino acids linked by a peptide bond. This compound serves as a key tool in the study of peptide synthesis and protein interactions. Its structural characteristics make it valuable for exploring various biochemical pathways and enhancing understanding of dipeptide functionality in biological systems. -
Peptide
CNSNQIC is a 7-amino acid peptide featuring a disulfide bridge between Cys1 and Cys7. This structural configuration provides stability and is crucial for its biological activity. It is primarily utilized in research focused on peptide interactions, protein folding, and structural biology studies. -
Cardioacceleratory Peptide
CAP2b is a cardioacceleratory peptide derived from Drosophila, known for its role in enhancing cardiac function. This peptide activates the cGMP signaling pathway, promoting tubule fluid secretion. CAP2b is primarily utilized in research exploring cardiovascular physiology and the mechanisms of peptidergic signaling in invertebrates. -
Cyclic Peptide
pPB peptide is a cyclic peptide that specifically targets the platelet-derived growth factor beta receptor (PDGFbR) with high affinity. This peptide can be utilized for PDGFbR-specific drug delivery applications, facilitating targeted therapeutic interventions in research settings. Its specificity makes it an invaluable tool for studying PDGFbR-related biological pathways and potential therapeutic implications. -
Peptide
Allotrap 2702 is a peptide that plays a crucial role in prolonging allograft survival. Its mechanism is important for modulating immune responses, making it a valuable tool for research in immunology. This compound can aid in the exploration of transplant rejection mechanisms and the development of therapies aimed at improving graft acceptance. -
FMRFamide-like Neuropeptide
Neuropeptide AF1 is a FMRFamide-like neuropeptide that demonstrates significant neuromodulatory activity in nematodes. Isolated from head extracts of Ascaris suum, Neuropeptide AF1 effectively abolishes slow membrane potential oscillations in both ventral and dorsal inhibitory motoneurons, while selectively decreasing their input resistances. This neuropeptide is useful for studying locomotion and inhibitory signaling in nematodes, making it a valuable tool for researchers investigating neurobiology and muscle control in invertebrates. -
Pentapeptide
CALNN is a pentapeptide that serves as a ligand for stabilizing and functionalizing gold nanoparticles, enhancing their utility in drug delivery applications. Its ability to facilitate the bio-conjugation of nanoparticles makes it a valuable tool in the development of targeted therapeutic systems. This compound is particularly useful in studies involving nanocarrier design and the optimization of drug delivery mechanisms. -
Renoprotective Peptide
Valyllysine (Val-Lys) is a renoprotective peptide that demonstrates significant protective effects against renal injury. Isolated from G. chorda soluble proteins through thermolysin hydrolysis, this compound has been shown to ameliorate pathological conditions in renal tissues. Valyllysine is valuable in research applications focused on kidney health and disease mechanisms. -
NLS-cell-penetrating Peptide
NLS-CPP is a nuclear localization signal (NLS)-cell-penetrating peptide derived from the NLS of OCT6, specifically designed to enhance nuclear delivery of biomolecules. This peptide is instrumental in facilitating the transport of therapeutic agents into the nucleus, thereby optimizing their biological efficacy. NLS-CPP has significant applications in research related to chronic inflammatory diseases, such as metabolic dysfunction-associated steatohepatitis (MASH) and osteoarthritis (OA). Its ability to promote nuclear uptake positions it as a valuable tool in drug delivery and cellular signaling studies. -
Tag peptide
SsrA tag is an 11-amino acid peptide that serves as a tag for proteins stalled during translation, facilitating their degradation by ClpXP and ClpAP proteases. This peptide is essential for studying protein quality control mechanisms and for investigating the dynamics of protein turnover within cells. Its application in research enhances understanding of cellular response to translational stress and the regulation of protein levels in various biological processes. -
Neuropeptide
Hym-355 is a neuropeptide derived from Hydra, known for its potent influence on oocyte maturation and spawning processes. This compound plays a crucial role in reproductive biology studies, enabling researchers to explore mechanisms of gametogenesis and hormonal regulation. Hym-355 serves as a valuable tool for examining neuropeptide signaling pathways and their effects on reproductive functions in aquatic organisms. -
β-sheet Peptide Foldamer
β4-TAT is a β-sheet peptide foldamer designed to target and influence the aggregation of fused in sarcoma (FUS) proteins by interacting with their RNA recognition motifs (RRM). Composed of a β4 sequence derived from the FUS RRM domain and a TAT sequence that facilitates nuclear localization, β4-TAT effectively induces FUS aggregation within cells, resulting in apoptosis of cancer cells. This reagent is valuable for research into FUS-related pathologies and the mechanisms underlying cancer cell death. -
Tag peptide
Avi Tag is a versatile short peptide tag designed for applications in protein expression and biotin labeling. This tag facilitates the site-specific attachment of biotin, enabling robust detection and purification of proteins using avidin or streptavidin-based methods. Its utility extends to various research applications, including functional assays, immunology studies, and protein-protein interaction investigations, enhancing experimental techniques in molecular biology. -
Artificially Designed Peptide
Decapeptide DP1 is an artificially designed peptide composed of ten amino acids (DEHGTAVMLK) that acts as a ligand to mimic components of the natural Mn²⁺ antioxidant complex. This peptide is integral in constructing the potent radiation protection agent MDP (Mn²⁺-DP1-Pi complex), demonstrating key biological activity in mitigating oxidative stress. Decapeptide DP1 is applicable in research focusing on antioxidant mechanisms and protective strategies against radiation-induced damage. -
Neuropeptide
Frog 26RFa is a neuropeptide derived from frog brain tissue, known for its pro-oxygen activity. This compound plays a significant role in neurobiology by modulating signaling pathways involved in various physiological processes. Research applications include studies on neuropeptide signaling, respiratory mechanisms, and potential therapeutic explorations in neurodegenerative diseases. -
T Cell Modulatory Peptide
Lysyl-serine is a T cell modulatory peptide known for its immunomodulatory properties. This compound plays a crucial role in enhancing T cell responses, making it valuable for research in immunology and potential therapeutic applications in autoimmune diseases and cancer. Its ability to modulate immune cell activity positions Lysyl-serine as a significant tool for studies focusing on the interplay between the immune system and disease. -
Mastoparan Family Peptide
Mastoparan-V1 is a peptide from the Mastoparan family that targets mast cells. It demonstrates moderate mast cell degranulation activity, with an EC50 of 130.24 μM in RBL-2H3 cells. This compound is useful for investigating mechanisms of allergic reactions, particularly those triggered by wasp stings. -
Neurohormones
Short Neuropeptide F is an insect neurohormone that primarily targets neurohormonal pathways. It plays a crucial role in modulating locomotor activity and regulating circadian rhythms in insects. This peptide is valuable for research applications focused on neurobiology, entomology, and the study of circadian systems. -
Bone-targeting Peptide
(Asp-Ser-Ser)6, also known as DSS6, is a synthetic bone-targeting peptide specifically designed to enhance bone tissue affinity. This compound serves as a ligand for modifying apoptotic extracellular vesicles (ApoEVs), thereby improving their targeting efficiency and therapeutic effectiveness in osteoporosis treatment. (Asp-Ser-Ser)6 is useful for research aimed at understanding and developing strategies for osteoporosis management. -
Polypeptide
Pyr-Gly-Arg-pNA is a synthetic substrate specifically designed for the enzyme tryptase, commonly found in guinea pig and human lung tissues. This compound exhibits key biological activity by facilitating the study of tryptase enzymatic activity, thereby contributing to research in inflammation and allergic responses. Its application in biochemical assays aids in the understanding of tryptase's role in various physiological and pathological processes. -
MHC class II epitope antigen
M30 peptide is an MHC class II epitope antigen that plays a crucial role in initiating T cell responses. This peptide is particularly valuable in cancer nanovaccine research, facilitating the development of targeted immunotherapies. By enhancing antigen presentation, M30 peptide supports investigations into adaptive immune responses against tumors. -
Immunomodulating Peptide
Thymotrinan is a biologically active fragment of the thymus hormone thymopoietin, functioning as an immunomodulating peptide. This compound exhibits immunomodulatory activities akin to TP5, influencing both humoral and cellular immune responses. Thymotrinan is suitable for research focused on immunoregulation and therapeutic applications in immune-related disorders. -
β-Lactoglobulin Peptide
VLVLDTDYK is a peptide derived from β-lactoglobulin, known for its role in protein structure and stability. This peptide exhibits significant binding affinity, making it useful in studies related to protein-protein interactions and stability analysis. Researchers can employ VLVLDTDYK in various applications, including protein engineering, functional assays, and understanding the structural dynamics of lactoglobulin in biological systems. -
Neuropeptide
Crinia-angiotensin II is a potent neuropeptide that plays a significant role in various physiological processes. Derived from the frog species Crinia Georgiana, this compound exhibits key biological activities relevant to neuroendocrine regulation. It acts primarily through modulation of the renin-angiotensin system and can be hydrolyzed by SedB, a tripeptidyl peptidase, making it a valuable tool for research applications in neurobiology and cardiovascular studies. -
MHC class I epitope antigen
M27 peptide is an MHC class I epitope antigen that plays a crucial role in immune response modulation. Its primary application lies in cancer nanovaccine research, facilitating the development of targeted immunotherapies. By presenting specific antigenic sequences, M27 peptide aids in the identification and activation of T lymphocytes, contributing to enhanced anti-tumor immune responses. -
Haemoregulatory Peptide
Glaspimod is a haemoregulatory peptide that functions by modulating blood flow and vascular permeability. It plays a crucial role in various biological processes, including inflammation and tissue repair. Research applications include studies on cardiovascular health, immune response, and the development of therapeutic strategies for related disorders. -
Peptide Segment
CLIKKPF is a specific peptide segment that binds with high affinity to phosphatidylserine (PS) located in the inner layer of the cell membrane. This unique interaction enhances the targeting ability of nanoparticles, making it a valuable tool in drug delivery systems. CLIKKPF is particularly relevant for research applications focused on cardiovascular conditions, facilitating insights into cell membrane dynamics and therapeutic interventions. -
HCC-targeting Peptide
SP94 peptide, Cys conjugated is a hepatocellular carcinoma (HCC)-targeting peptide designed to facilitate the synthesis of stimuli-responsive peptide nanomaterials. Its primary mechanism involves promoting the endocytosis of platinum nanocluster assemblies, enhancing their uptake in HCC cells. This peptide is valuable for cancer research, particularly in developing targeted drug delivery systems for hepatocellular carcinoma therapies. -
Generic surrogate peptide
TTP is a generic surrogate peptide that serves as a standard for quantitative analysis of recombinant human immunoglobulin G1 (hIgG1) in rat serum samples. This peptide facilitates accurate measurement and is essential for studies involving pharmacokinetics, immunogenicity assessments, and the development of therapeutic antibodies in preclinical research. Its application in quantitative assays enhances the reliability of experimental outcomes in the field of biotherapeutics. -
Self-assembling Peptide
RAD-FHR peptide is a self-assembling peptide that enhances migration, proliferation, and growth factor secretion in human adipose stem cells (hASCs). This peptide facilitates the synthesis of nanofiber hydrogels, making it a valuable tool for investigating stem cell behaviors within biomimetic 3D systems. Its unique properties support various applications in tissue engineering and regenerative medicine research. -
Radiotracer
NOTA-NOC is a peptide-based radiotracer that binds to somatostatin receptors, enabling its use in positron emission tomography/computed tomography (PET/CT) imaging. This compound is primarily utilized for the diagnosis and monitoring of neuroendocrine tumors, providing critical information on tumor localization and progression. Its high specificity facilitates targeted imaging, contributing to improved patient management and treatment outcomes in oncology. -
Neuropeptide
Allatostatin C (AstC) is a neuropeptide that primarily targets the suppression of gonadotropin production. It plays a crucial role in regulating the oogenesis rhythm by modulating juvenile hormone and vitellogenesis through insulin signaling pathways. This compound is valuable for neurological research and studies investigating neuropeptide functions in reproductive biology. -
Nuclear Localization Signal Peptide
NLS Peptide is a nuclear localization signal peptide that facilitates the transport of conjugated molecules and nanoparticles into the nucleus via interaction with the nuclear transport machinery, including Importin protein complexes. The peptide's N-terminal Cys terminus allows for convenient coupling with various entities. NLS Peptide is valuable for constructing nucleus-specific imaging probes and targeted nanoparticles, making it an important tool for researchers in cell biology and drug delivery applications.
