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Phloretin inhibits the active transport of glucose into cells by SGLT1 and SGLT2, though the inhibition is weaker than by its glycoside phlorizin.
Targets
| SGLT1 | SGLT2 | |||
| In vitro | DMSO | 55 mg/mL (200.53 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 55 mg/mL (200.53 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.46 mL | 182.28 mL | 364.56 mL |
| 0.5 mM | 7.29 mL | 36.46 mL | 72.91 mL |
| 1 mM | 3.65 mL | 18.23 mL | 36.46 mL |
| 5 mM | 0.73 mL | 3.65 mL | 7.29 mL |
*The above data is based on the productmolecular weight 274.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A10723 |
|---|---|
| Actions | N/A |
| M. Wt | 274.3 |
| Formula | C15H14O5 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 60-82-2 |
| Synonyms | Dihydronaringenin, Phloretol |
| SMILES | C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O |
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