Phloretin (Dihydronaringenin)

Catalog No.: A10723

Phloretin (Dihydronaringenin)

Phloretin (Dihydronaringenin) Chemical Structure

CAS NO. 60-82-2

Phloretin inhibits the active transport of glucose into cells by SGLT1 and SGLT2, though the inhibition is weaker than by its glycoside phlorizin.

Availability: In stock

Package Price Qty
250 mg
$40.00
500 mg
$65.00
1000 mg
$100.00
10mM * 1mL in DMSO
$59.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Subramaniam M, .et al. Comparison of Intestinal Glucose Flux and Electrogenic Current Demonstrates Two Absorptive Pathways in Pig and One in Nile Tilapia and Rainbow Trout, Am J Physiol Regul Integr Comp Physiol, 2019, Nov 20 PMID: 31746628

Biological Activity

Phloretin inhibits the active transport of glucose into cells by SGLT1 and SGLT2, though the inhibition is weaker than by its glycoside phlorizin.
Targets
SGLT1 SGLT2
In vitro DMSO 46 mg/mL (167.71 mM)
Water Insoluble
Ethanol 46 mg/mL (167.71 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.46 mL 182.28 mL 364.56 mL
0.5 mM 7.29 mL 36.46 mL 72.91 mL
1 mM 3.65 mL 18.23 mL 36.46 mL
5 mM 0.73 mL 3.65 mL 7.29 mL

*The above data is based on the productmolecular weight 274.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10723
CAS No. 60-82-2
Formula C15H14O5
M. Wt 274.3
Purity >98%
Synonyms Dihydronaringenin, Phloretol
SMILES C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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