Phthalimide-PEG3-C2-OTs

Catalog No.: A83075
PROTAC Linkers
Phthalimide-PEG3-C2-OTs is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a phthalimide moiety connected by a polyethylene glycol (PEG) chain, enabling effective linkage between ligands that bind to E3 ubiquitin ligases and target proteins. By harnessing the ubiquitin-proteasome system, PROTACs equipped with Phthalimide-PEG3-C2-OTs promote selective degradation of specific proteins, making it a valuable tool for targeted protein modulation in various biological research applications.
Grouped product items
Size Price Stock Qty
25mg
$65.00
In stock
50mg
$95.00
In stock
100mg
$140.00
In stock
250mg
$250.00
In stock
1g
$700.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPhthalimide-PEG3-C2-OTs is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a phthalimide moiety connected by a polyethylene glycol (PEG) chain, enabling effective linkage between ligands that bind to E3 ubiquitin ligases and target proteins. By harnessing the ubiquitin-proteasome system, PROTACs equipped with Phthalimide-PEG3-C2-OTs promote selective degradation of specific proteins, making it a valuable tool for targeted protein modulation in various biological research applications.
Product Information
Catalog NumA83075
FormulaC23H27NO8S
Molecular Weight477.53
CAS Number382162-12-1
SMILESCC(C=C1)=CC=C1S(=O)(OCCOCCOCCOCCN2C(C3=C(C=CC=C3)C2=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2