Phthalimide-PEG3-C2-OTs is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a phthalimide moiety connected by a polyethylene glycol (PEG) chain, enabling effective linkage between ligands that bind to E3 ubiquitin ligases and target proteins. By harnessing the ubiquitin-proteasome system, PROTACs equipped with Phthalimide-PEG3-C2-OTs promote selective degradation of specific proteins, making it a valuable tool for targeted protein modulation in various biological research applications.
Phthalimide-PEG3-C2-OTs is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a phthalimide moiety connected by a polyethylene glycol (PEG) chain, enabling effective linkage between ligands that bind to E3 ubiquitin ligases and target proteins. By harnessing the ubiquitin-proteasome system, PROTACs equipped with Phthalimide-PEG3-C2-OTs promote selective degradation of specific proteins, making it a valuable tool for targeted protein modulation in various biological research applications.
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