PKUMDL-LTQ-301

Catalog No.: A47184
Antibiotic
PKUMDL-LTQ-301 is a HipA toxin inhibitor that disrupts bacterial persistence by targeting the HipA protein in Escherichia coli. This compound has demonstrated significant reduction in bacterial survival rates in both in vitro and in vivo models, making it a valuable tool for antibiotic research. PKUMDL-LTQ-301's efficacy is supported by specific KD and EC50 values, underscoring its potential in studies focused on overcoming antibiotic resistance and developing novel antibacterial therapies.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPKUMDL-LTQ-301 is a HipA toxin inhibitor that disrupts bacterial persistence by targeting the HipA protein in Escherichia coli. This compound has demonstrated significant reduction in bacterial survival rates in both in vitro and in vivo models, making it a valuable tool for antibiotic research. PKUMDL-LTQ-301's efficacy is supported by specific KD and EC50 values, underscoring its potential in studies focused on overcoming antibiotic resistance and developing novel antibacterial therapies.
Product Information
Catalog NumA47184
FormulaC30H28N2O4
Molecular Weight480.55
CAS Number728886-01-9
SMILESO=C(C1=C(C(N(C1C2=CC=C(CC)C=C2)CCC3=CNC4=C3C=CC=C4)=O)O)C5=CC=C(C=C5)OC
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