Platencin is a natural broad-spectrum antibiotic derived from Streptomyces platensis. It primarily targets β-ketoacyl-ACP synthases II and III (FabF and FabH), inhibiting their activity with IC50 values of 1.95 and 3.91 μg/ml, respectively. This compound exhibits potent antibacterial activity against Gram-positive bacteria and is of significant interest for research in antibiotic development and resistance.
Platencin is a natural broad-spectrum antibiotic derived from Streptomyces platensis. It primarily targets β-ketoacyl-ACP synthases II and III (FabF and FabH), inhibiting their activity with IC50 values of 1.95 and 3.91 μg/ml, respectively. This compound exhibits potent antibacterial activity against Gram-positive bacteria and is of significant interest for research in antibiotic development and resistance.
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