Plerixafor 8HCl (DB06809)

Catalog No.: A10913

CXCR4 antagonist

Plerixafor 8HCl (DB06809)

Plerixafor 8HCl (DB06809) Chemical Structure

CAS NO. 155148-31-5

Plerixafor is an immunostimulant used to multiply hematopoietic stem cells and it is a chemokine receptor-4 antagonist for mobilization of hematopoietic stem cells for transplantation.

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10 mg
$60.00
25 mg
$100.00
50 mg
$160.00
100 mg
$310.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Asiedu KO, .et al. Bone marrow cell homing to sites of acute tibial fracture: 89Zr-oxine cell labeling with positron emission tomographic imaging in a mouse model., EJNMMI Res, 2018, Dec 13;8(1):109 PMID: 30547233
  • Kingsley O. Asiedu, .et al. Bone marrow cell trafficking analyzed by 89Zr-oxine positron emission tomography in a murine transplantation model, Clin Cancer Res, 2017, Jun 1; 23(11): 2759-2768 PMID: 27965305

Biological Activity

Plerixafor is an immunostimulant used to multiply hematopoietic stem cells and it is a chemokine receptor-4 antagonist for mobilization of hematopoietic stem cells for transplantation.
Targets
CXCL12-mediated chemotaxis (Cell-free assay) CXCR4 (Cell-free assay)
5.7 nM44 nM
In vitro (25°C) DMSO Insoluble
Water 91 mg/mL (114.54 mM)
Ethanol Insoluble
In vivo Saline 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.59 mL 62.93 mL 125.87 mL
0.5 mM 2.52 mL 12.59 mL 25.17 mL
1 mM 1.26 mL 6.29 mL 12.59 mL
5 mM 0.25 mL 1.26 mL 2.52 mL

*The above data is based on the productmolecular weight 794.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10913
Actions Antagonist
CAS No. 155148-31-5
Formula C28H54N8.8HCl
M. Wt 794.5
Solubility DMSO
Purity >98%
Synonyms DB06809, AMD3100, Mozobil
SMILES C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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