PM534 is a tubulin-targeting agent that inhibits tubulin assembly with IC50 values ranging from 0.8 to 3.2 nM. By binding to the colchicine site of tubulin, PM534 disrupts microtubule dynamics, demonstrating significant antitumor activity. This compound is valuable for research applications in cancer biology, particularly in studies focused on cell division and microtubule-targeting therapies.
PM534 is a tubulin-targeting agent that inhibits tubulin assembly with IC50 values ranging from 0.8 to 3.2 nM. By binding to the colchicine site of tubulin, PM534 disrupts microtubule dynamics, demonstrating significant antitumor activity. This compound is valuable for research applications in cancer biology, particularly in studies focused on cell division and microtubule-targeting therapies.
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