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Pneumocandin A4

Catalog No.: A47780
Antibiotic
Pneumocandin A4 is a lipopeptide antibiotic that targets the synthesis of 1,3-β-glucan, crucial for fungal cell wall integrity. It exhibits significant antifungal activity against Candida species, demonstrating an IC50 range of 0.07-0.5 μg/mL in vitro. This compound is valuable for research applications focused on antifungal mechanisms and the development of new therapeutic agents against fungal infections.
Pneumocandin A4 135882-23-4 Antibiotic
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPneumocandin A4 is a lipopeptide antibiotic that targets the synthesis of 1,3-β-glucan, crucial for fungal cell wall integrity. It exhibits significant antifungal activity against Candida species, demonstrating an IC50 range of 0.07-0.5 μg/mL in vitro. This compound is valuable for research applications focused on antifungal mechanisms and the development of new therapeutic agents against fungal infections.
Product Information
Catalog NumA47780
FormulaC51H82N8O13
Molecular Weight1015.24
CAS Number135882-23-4
SMILESCC[C@@H](C[C@@H](CCCCCCCCC(N[C@@H]1CCCNC([C@@H]2[C@@H](O)[C@@H](C)CN2C([C@H]([C@H](O)CC(N)=O)NC([C@H](CCC3=CC=C(O)C=C3)NC([C@@H]4C[C@@H](O)CN4C([C@H]([C@H](O)C)NC1=O)=O)=O)=O)=O)=O)=O)C)C
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Calculate the dilution required to prepare a stock solution.
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Microbiology > Antifection > Antibiotic