Propargyl-PEG2-acid

Catalog No.: A42711
PROTAC/ADC Linker
Propargyl-PEG2-acid is a non-cleavable linker targeting the synthesis of antibody-drug conjugates (ADCs) and PROTACs. This PEG-based compound facilitates the conjugation process through click chemistry, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. It serves as a vital tool for researchers in the development of innovative therapeutic strategies involving ADCs and targeted protein degradation applications.
Grouped product items
Size Price Stock Qty
100mg
$60.00
In stock
250mg
$110.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPropargyl-PEG2-acid is a non-cleavable linker targeting the synthesis of antibody-drug conjugates (ADCs) and PROTACs. This PEG-based compound facilitates the conjugation process through click chemistry, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. It serves as a vital tool for researchers in the development of innovative therapeutic strategies involving ADCs and targeted protein degradation applications.
Product Information
Catalog NumA42711
FormulaC8H12O4
Molecular Weight172.18
CAS Number1859379-85-3
SMILESO=C(O)CCOCCOCC#C
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