Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite functions as a PEG-based linker for protein degradation technologies, specifically PROTAC synthesis. This compound includes an alkyne functionality that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling efficient conjugation with azide-containing partners. It is suitable for applications in targeted protein degradation studies and offers versatility in the development of innovative therapeutic modalities.
Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite functions as a PEG-based linker for protein degradation technologies, specifically PROTAC synthesis. This compound includes an alkyne functionality that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling efficient conjugation with azide-containing partners. It is suitable for applications in targeted protein degradation studies and offers versatility in the development of innovative therapeutic modalities.
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