Propargyl-PEG5-azide is a PEG-based linker designed for antibody-drug conjugate (ADC) and PROTAC applications. This compound features an azide functional group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Propargyl-PEG5-azide can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile and effective tool for chemical biologists developing targeted therapeutics.
Propargyl-PEG5-azide is a PEG-based linker designed for antibody-drug conjugate (ADC) and PROTAC applications. This compound features an azide functional group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Propargyl-PEG5-azide can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile and effective tool for chemical biologists developing targeted therapeutics.
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