Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
Potassium (2-benzyloxyethyl)trifluoroborate functions as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound is integral to the development of innovative therapeutic strategies that selectively degrade target proteins through the ubiquitin-proteasome system. Its ability to enhance target specificity and efficacy makes it a valuable reagent for researchers in drug discovery and protein biology. -
PROTAC Linker
1-Bromo-4-(3-bromopropyl)benzene serves as a crucial linker in the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the development of novel targeted degradation therapies by enabling the conjugation of target proteins to E3 ubiquitin ligases. Its application is significant in research focused on elucidating cellular mechanisms and exploring therapeutic strategies for various diseases, including cancer. -
PROTAC Linker
16-Methoxy-16-oxohexadecanoic acid is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). Its chemical structure allows for efficient conjugation to target proteins, enabling selective degradation pathways. This reagent is essential for research applications focused on exploring targeted protein degradation mechanisms and developing novel therapeutics. -
PROTAC Linker
Boc-piperidin-C-COOH is a versatile PROTAC linker that facilitates the development of targeted protein degradation molecules. By serving as a bridge between an E3 ligase ligand and a protein target, it enhances the specificity and efficacy of PROTACs. This compound is essential for researchers aiming to explore protein modulation and degradation pathways in cellular studies. -
PROTAC Linker
1-Bromo-3-(3-bromopropoxy)propane is a versatile PROTAC linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the formation of bifunctional molecules that recruit E3 ligases for targeted protein degradation. Its unique structure allows for optimized interaction with specific biological targets, making it invaluable for research in drug discovery and therapeutic development. -
PROTAC Linker
3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid hydrochloride serves as a PROTAC linker, facilitating the development of heterobifunctional molecules for targeted protein degradation. This compound plays a critical role in the synthesis of PROTACs, enabling the selective modulation of protein activity within cellular pathways. Its unique structural properties make it a valuable tool in chemical biology and therapeutic research applications aimed at degrading specific proteins associated with various diseases. -
PROTAC Linkers
Thiol-PEG8-alcohol is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features a thiol group, facilitating conjugation to target proteins while enhancing solubility and stability. Its application is essential in the development of novel therapeutic agents that induce targeted degradation of specific proteins, thus enabling innovative strategies in cellular biology and drug discovery. -
PROTAC Linker
1,18-Dibromooctadecane serves as a PROTAC linker, facilitating the development of targeted protein degradation agents. Its unique structure allows for the effective conjugation of protein-targeting moieties with E3 ligase ligands, enhancing the specificity and efficacy of PROTAC compounds. This linker is instrumental in advancing research focused on proteolysis-targeting chimeras and their therapeutic applications in various diseases. -
PROTAC Linker
3-(4-Bromophenyl)propan-1-ol serves as an effective PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins by linking E3 ligases to the desired protein of interest, thereby enhancing the efficiency of targeted protein modulation in research settings. Its utility in PROTAC development supports investigations into protein interactions, degradation pathways, and therapeutic approaches in various disease models. -
PROTAC Linker
tert-Butyl 4-(piperidine-4-carbonyl)piperazine-1-carboxylate is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of targeted protein degradation strategies by linking E3 ligases to specific protein targets. Its incorporation into PROTAC constructs is essential for enhancing selectivity and efficacy in various biological research applications, including drug discovery and cancer therapeutics. -
PROTAC Linker
Pent-4-yn-1-amine hydrochloride serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is integral in the synthesis of PROTACs, which enable selective degradation of target proteins, offering innovative approaches in drug discovery and therapeutic applications. Researchers can utilize this linker to enhance the efficacy and specificity of their PROTAC-based designs. -
PROTAC Linker
5-Bromovaleronitrile serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficiency of targeted protein degradation by promoting the formation of stable complexes between E3 ligases and substrates. Its utility in chemical biology research underscores its significance in exploring novel therapeutic avenues in cancer and other diseases characterized by protein dysregulation. -
PROTAC Linker
2-Iodoethanol is a versatile PROTAC linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the formation of covalent bonds between target proteins and ubiquitin ligases, enabling targeted protein degradation. Its application in chemical biology and drug discovery makes it a valuable tool for researchers studying protein function and regulation. -
PROTAC Linker
4-(2-Bromoethyl)benzonitrile serves as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the creation of bifunctional molecules that selectively degrade target proteins, making it valuable for research in targeted protein degradation and therapeutic applications. Its availability allows for the exploration of innovative approaches to modulate protein levels in various biological systems. -
PROTAC Linker
tert-Butyl hept-6-yn-1-ylcarbamate is a PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound enables selective degradation of target proteins through the recruitment of E3 ligases, thereby modulating cellular pathways. It is valuable for research in drug discovery and the investigation of protein function in various biological contexts. -
PROTAC Linker
PEG2-Dichloride functions as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). Its unique structure enhances the conjugation efficiency between target proteins and E3 ligases, promoting targeted protein degradation. This compound is essential for researchers developing PROTACs to probe cellular functions or therapeutic applications in drug discovery. -
PROTAC Linker
Fmoc-9-Aminononanoic acid functions as a PROTAC linker, featuring a terminal Fmoc-protected amine and a carboxylic acid group. This compound is instrumental in the synthesis of PROTACs and other conjugation applications. The Fmoc group is removable under basic conditions, yielding a free amine suitable for further conjugations. Additionally, the carboxylic acid can readily engage with primary amines in the presence of coupling agents such as EDC or HATU, facilitating the formation of stable amide bonds for diverse biochemical applications. -
PROTAC Linker
tert-Butyl (cis-3-(hydroxymethyl)cyclobutyl)carbamate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in creating targeted protein degradation systems to enhance the specificity and efficacy of therapeutic agents. Its unique structure allows for effective molecular coupling, making it valuable in chemical biology research and drug discovery applications. -
PROTAC Linker
3-Aminobicyclo[1.1.1]pentane-1-carbonitrile serves as a versatile PROTAC linker, facilitating the development of targeted protein degraders. Its unique structure enhances the efficiency of PROTAC synthesis, enabling precise modulation of protein activity in cellular systems. This compound is essential for researchers focused on targeted protein degradation and therapeutic applications in oncology and other disease models. -
PROTAC Linker
tert-Butyl (3-(3-aminopropoxy)propyl)carbamate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins, advancing research in targeted protein modulation. Its application is essential in the synthesis of innovative PROTACs to explore novel therapeutic approaches in drug discovery and cellular biology. -
PROTAC Linker
Hept-6-yn-1-amine is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This reagent provides a unique alkyne functionality that enhances the coupling of the protein ligands, enabling targeted degradation of specific proteins within the cell. Its efficient linkage properties make it a valuable tool for researchers exploring targeted protein modulation and degradation pathways in pharmacological studies. -
PROTAC Linker
tert-Butyl 11-bromoundecanoate functions as a PROTAC linker, facilitating the construction of Proteolysis Targeting Chimeras (PROTACs). This compound enhances the efficiency of targeted protein degradation by enabling the conjugation of E3 ligase ligands to the target protein. It is instrumental in drug discovery and development, particularly in studies aimed at regulating protein levels for therapeutic purposes. -
PROTAC Linker
tert-Butyl N-[3-(tetramethyl-1,3,2-dioxaborolan-2-yl)propyl]carbamate functions as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of targeted protein degradation applications, contributing to advancements in therapeutic research. Its unique structural properties enable effective conjugation with target proteins, making it a valuable tool in drug discovery and development efforts. -
PROTAC Linker
tert-Butyl 4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by linking ligands to E3 ubiquitin ligases. Its application in PROTAC development supports research in targeted protein degradation, offering insights into proteostasis and therapeutic interventions. -
PROTAC Linker
1,9-Diaminononane serves as a versatile linker for PROTAC (Proteolysis Targeting Chimeras) synthesis. It facilitates the conjugation of target proteins to E3 ligases, enabling targeted protein degradation. This compound is essential in the development of novel therapeutic strategies aimed at modulating protein levels in various biological systems. -
PROTAC Linker
Tert-butyl 4-(2-bromoethyl)piperidine-1-carboxylate serves as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound enhances the development of targeted protein degradation strategies, enabling researchers to investigate cellular pathways and protein interactions. Its key biological applications include elucidating the roles of specific proteins in various disease models and advancing targeted therapeutic approaches. -
PROTAC Linker
7-Methoxy-7-oxoheptanoic acid is a biochemical linker utilized in the development of PROTAC (Proteolysis Targeting Chimera) molecules. This compound enhances the stability and effectiveness of PROTACs by facilitating the interaction between the E3 ligase and the target protein, ultimately leading to targeted degradation. It is valuable in drug discovery and therapeutic research focused on modulating protein levels in cellular systems. -
PROTAC Linker
3-(4-Iodophenyl)propanoic acid serves as a versatile PROTAC linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the design of bifunctional molecules that can selectively induce the degradation of target proteins via the ubiquitin-proteasome pathway. Its unique structural properties enable effective conjugation to various target ligands, making it a valuable tool for researchers investigating targeted protein degradation and related therapeutic strategies. -
PROTAC Linker
Methyl 2-(4-(aminomethyl)phenyl)acetate hydrochloride is a PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins, making it a valuable tool in cellular and molecular biology research. Its involvement in synthetic methodologies allows for the efficient design and optimization of targeted protein degradation strategies. -
PROTAC Linker
N-(3-Aminopropyl)-N-methylcarbamic acid tert-butyl ester serves as a PROTAC linker, facilitating the design and synthesis of targeted protein degradation (PROTAC) molecules. Its unique structure enables effective conjugation of targeting ligands, enhancing the efficiency of PROTAC applications in drug discovery and development. This compound is essential for studies aimed at understanding cellular regulation and protein turnover mechanisms. -
PROTAC Linker
Br-CO-piperazine-Boc is a versatile PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimera (PROTAC) compounds. Its unique structure enhances the ability to engage in selective protein degradation, making it an essential reagent for researchers exploring targeted protein modulation and degradation pathways. This compound is highly applicable in drug discovery and development, specifically for the development of novel therapeutic agents that can regulate protein levels in disease models. -
PROTAC Linker
4-((tert-Butyldimethylsilyl)oxy)butan-1-ol functions as a versatile PROTAC linker. It plays a critical role in the synthesis of Proteolysis Targeting Chimeras (PROTACs), enabling the targeted degradation of proteins. This compound is essential for researchers investigating protein interactions and developing novel therapeutic strategies through targeted protein modulation. -
PROTAC Linker
6-Aminohexanenitrile is a versatile PROTAC linker that facilitates the development of targeted protein degradation technologies. Its unique structure allows for effective conjugation with active targeting moieties and effector proteins, enhancing the specificity and efficacy of PROTACs. This compound is essential for researchers aiming to explore protein modulation and degradation pathways in drug discovery and therapeutic applications. -
PROTAC Linker
2-[3-(Methoxycarbonyl)bicyclo[1.1.1]pentan-1-yl]acetic acid functions as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of targeted protein degradation by linking E3 ligases to the target proteins, allowing for precise modulation of cellular pathways. It is a valuable tool for researchers investigating the mechanisms of protein degradation and developing novel therapeutic interventions in various diseases. -
PROTAC Linker
tert-Butyl ((4-oxocyclohexyl)methyl)carbamate functions as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). Its structural features enhance target specificity and binding efficiency, making it an essential component in the development of targeted protein degradation strategies. This chemical is widely utilized in research focused on protein regulation and therapeutic development. -
PROTAC Linker
2-[2-(tert-Butoxy)-2-oxoethoxy]acetic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in the synthesis of targeted protein degraders, enabling the selective modulation of protein levels within cellular environments. It is valuable for researchers engaged in the exploration of targeted therapy and drug discovery. -
PROTAC Linker
4-Hydroxybicyclo[2.2.2]octane-1-carboxylic acid serves as a versatile PROTAC linker. It facilitates the design and synthesis of PROTAC molecules aimed at targeted protein degradation. This compound is instrumental in advancing research in targeted therapies and elucidating cellular processes through the modulation of specific protein levels. -
PROTAC Linker
Z-Glycinol is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligases, enhancing the targeted degradation of selected proteins within cellular systems. Its application in PROTAC development enables innovative approaches in drug discovery and therapeutic intervention. -
PROTAC Linker
tert-Butyl 4-(methylamino)butanoate hydrochloride serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the development of targeted protein degradation strategies, enabling researchers to investigate protein functions and develop novel therapeutic interventions. Its unique structural features contribute to linker stability and optimal binding specificity in PROTAC applications. -
PROTAC Linker
tert-Butyl (E)-4-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)piperidine-1-carboxylate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enables the conjugation of ligands to proteins, enhancing the targeted degradation of specific proteins in cellular systems. Its application is crucial in drug discovery and development, particularly in oncology and therapeutic resistance research. -
PROTAC Linker
3-(4-Bromophenyl)propanoic acid functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the synthesis of PROTACs, enabling the targeted degradation of specific proteins. Its unique chemical properties make it valuable in research focused on protein modulation and therapeutic intervention in various diseases. -
PROTAC Linker
AMCA (4-(Aminomethyl)-1-cyclohexanecarboxylic acid) serves as a versatile PROTAC linker, facilitating the development of targeted protein degradation compounds. It is utilized in the synthesis of the PROTAC molecule YB-3–17, which plays a significant role in studying protein degradation pathways and therapeutic interventions. This reagent is essential for researchers focusing on the design and implementation of PROTAC-based strategies in molecular biology and drug discovery. -
PROTAC Linker
m-PEG6-CH2CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates targeted protein degradation by connecting an E3 ligase ligand to a target protein ligand, aiding in the development of innovative therapeutic strategies. It is particularly valuable in drug discovery and development for the modulation of protein levels in cellular and animal models. -
PROTAC Linker
NH-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound enhances solubility and flexibility, facilitating efficient ubiquitination and degradation of target proteins. NH-bis(PEG4-acid) is ideal for researchers developing novel PROTAC molecules in various therapeutic applications, including targeted protein degradation and drug discovery. -
PROTAC Linkers
Tetraethyl octane-1,8-diylbis(phosphonate) is an alkyl chain-based linker designed for the development of PROTACs (proteolysis targeting chimeras). This compound facilitates the assembly of protein-targeting small molecules, promoting targeted degradation of specific proteins within cells. Its structural properties support the formation of efficient PROTACs, making it a valuable tool in chemical biology and therapeutic research for investigating protein functions and therapeutic interventions. -
PROTAC Linker
Bromo-PEG1-CH2COOH is a versatile PROTAC linker that facilitates the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables selective degradation of target proteins by linking an E3 ligase ligand to a target protein binder through a PEG spacer. Its application is crucial in drug discovery and development, particularly for studies focused on targeted protein degradation and novel therapeutic interventions. -
PROTAC Linkers
Amino-PEG4-C1-Boc is a polyethylene glycol (PEG)-based linker specifically designed for Protein Targeting Chimeras (PROTACs). This compound facilitates the synthesis of PROTACs by providing a flexible and biocompatible spacer that enhances solubility and stability. Its application is vital in the field of targeted protein degradation research, enabling the development of novel therapeutics that modulate protein function through ubiquitin-proteasome pathway engagement. -
PROTAC Linkers
Boc-NH-PEG15-NH2 is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the formation of covalent bonds between target proteins and E3 ligases, enhancing targeted degradation of specific proteins within cells. Its PEG structure provides increased solubility and improved pharmacokinetic properties, making it valuable in chemical biology and drug development applications focused on targeted protein degradation. -
PROTAC Linker
NH2-PEG3-C6-Cl is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the assembly of targeting warheads and E3 ligase recruiters, enhancing the degradation of specific proteins within cells. Its application in PROTAC development supports research into targeted protein degradation, offering potential therapeutic advantages in various diseases. -
PROTAC Linker Chemical
1-Bromo-6-chlorohexane is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). Its chemical structure is designed to promote the efficient recruitment of E3 ubiquitin ligases, enhancing targeted protein degradation. This compound is essential for researchers investigating the regulation of protein homeostasis and the therapeutic potential of targeted protein degradation strategies.
