PX-866 (Sonolisib)

Catalog No.: A11261

PI3K inhibitor

PX-866 (Sonolisib)

PX-866 (Sonolisib) Chemical Structure

CAS NO. 502632-66-8

PX-866 is a small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $150.00

Special Price $120.00

10 mg

Regular Price: $260.00

Special Price $208.00

25 mg

Regular Price: $450.00

Special Price $360.00

50 mg

Regular Price: $700.00

Special Price $560.00

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Biological Activity

PX-866 is a small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential antineoplastic activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.04 mL 95.2 mL 190.4 mL
0.5 mM 3.81 mL 19.04 mL 38.08 mL
1 mM 1.9 mL 9.52 mL 19.04 mL
5 mM 0.38 mL 1.9 mL 3.81 mL

*The above data is based on the productmolecular weight 525.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11261
Actions Inhibitor
CAS No. 502632-66-8
Formula C29H35NO8
M. Wt 525.2
Solubility DMSO
Purity >98%
Synonyms PX866
SMILES O=C(/C1=C\N(CC=C)CC=C)O[[email protected]](COC)[[email protected]@]2(C)C1=C(O)C(C3=C2[[email protected]](OC(C)=O)C[[email protected]@]4(C)[[email protected]@]3([H])CCC4=O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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