Wortmannin

Catalog No.: A11161
PI3K inhibitor

Wortmannin is a potent, selective, cell-permeable and irreversible inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) (IC50 = 2 - 4 nM) which also potently inhibits polo-like kinase 1 (PLK1) (IC50 = 5.8 nM).

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Product Name Price Stock Qty
Wortmannin 5mg
Special Price $64.00 Regular Price $80.00
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Wortmannin 10mg
Special Price $88.00 Regular Price $110.00
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Wortmannin 25mg
Special Price $192.00 Regular Price $240.00
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Wortmannin 50mg
Special Price $304.00 Regular Price $380.00
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Wortmannin 10mM * 1mL in DMSO
Special Price $68.00 Regular Price $85.00
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Adooq Products cited in reputable paper
Adooq's Wortmannin has been cited by 1 publications
  • Hirotake Ishida, .et al. , J Neurosci, 2021, Oct 13;41(41):8494-8507 PMID: 34452938
  • Biological Activity
    Discription

    Wortmannin is a potent, selective, cell-permeable and irreversible inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) (IC50 = 2 - 4 nM) which also potently inhibits polo-like kinase 1 (PLK1) (IC50 = 5.8 nM).

    Targets
    Target Value
    Product Information
    Catalog Num A11161
    Formula C23H24O8
    Molecular Weight 428.43
    CAS Number 19545-26-7
    SMILES CC(=O)O[C@@H]1C[C@]2([C@@H](CCC2=O)C3=C1[C@]4([C@H](OC(=O)C5=COC(=C54)C3=O)COC)C)C
    Synonyms SL-2052
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 73 mg/mL (170.38 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+40% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.34 mL 116.71 mL 233.41 mL
    0.5 mM 4.67 mL 23.34 mL 46.68 mL
    1 mM 2.33 mL 11.67 mL 23.34 mL
    5 mM 0.47 mL 2.33 mL 4.67 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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