Pyrene azide 3 is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing compounds, making it versatile for targeted protein degradation applications in chemical biology research.
Pyrene azide 3 is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing compounds, making it versatile for targeted protein degradation applications in chemical biology research.
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