Q-VD-OPh hydrate

Catalog No.: A14915

Caspase inhibitor

Q-VD-OPh hydrate Chemical Structure

CAS NO. 1135695-98-5

Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM).

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$150.00
25 mg
$240.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM).
Targets
Caspase-1 Caspase-3 Caspase-8 Caspase-9
25 nM-400 nM25 nM-400 nM25 nM-400 nM25 nM-400 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.47 mL 97.37 mL 194.75 mL
0.5 mM 3.89 mL 19.47 mL 38.95 mL
1 mM 1.95 mL 9.74 mL 19.47 mL
5 mM 0.39 mL 1.95 mL 3.89 mL

*The above data is based on the productmolecular weight 513.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14915
Actions Inhibitor
M. Wt 513.49
Formula C26H25F2N3O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1135695-98-5
Synonyms N/A
SMILES CC(C)C(C(=O)NC(CC(=O)O)C(=O)COC1=C(C=CC=C1F)F)NC(=O)C2=NC3=CC=CC=C3C=C2

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