(R)-GSK-3685032 is a reversible inhibitor selectively targeting DNMT1, exhibiting a non-time-dependent and noncovalent mechanism of action. With an IC50 value of 0.036 μM, it effectively induces significant loss of DNA methylation and promotes transcriptional activation. This compound is suitable for research applications exploring epigenetic modifications in cancer biology, particularly in studies focused on cancer cell growth inhibition.
(R)-GSK-3685032 is a reversible inhibitor selectively targeting DNMT1, exhibiting a non-time-dependent and noncovalent mechanism of action. With an IC50 value of 0.036 μM, it effectively induces significant loss of DNA methylation and promotes transcriptional activation. This compound is suitable for research applications exploring epigenetic modifications in cancer biology, particularly in studies focused on cancer cell growth inhibition.
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