R306465

Catalog No.: A15437

HDAC inhibitor

R306465

R306465 Chemical Structure

CAS NO. 604769-01-9

R306465 is a novel hydroxamate-based histone deacetylase (HDAC) inhibitor with broad-spectrum antitumour activity against solid and haematological malignancies in preclinical models.

Availability: In stock

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2 mg

Regular Price: $200.00

Special Price $160.00

5 mg

Regular Price: $350.00

Special Price $280.00

10 mg

Regular Price: $650.00

Special Price $520.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Mari Ishigami-Yuasa, .et al. Class IIb HDAC Inhibition Enhances the Inhibitory Effect of Am80, a Synthetic Retinoid, in Prostate Cancer, Biol Pharm Bull, 2019, 42, 448-452

Biological Activity

R306465 is a novel hydroxamate-based histone deacetylase (HDAC) inhibitor with broad-spectrum antitumour activity against solid and haematological malignancies in preclinical models.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.19 mL 120.93 mL 241.87 mL
0.5 mM 4.84 mL 24.19 mL 48.37 mL
1 mM 2.42 mL 12.09 mL 24.19 mL
5 mM 0.48 mL 2.42 mL 4.84 mL

*The above data is based on the productmolecular weight 413.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15437
Actions Inhibitor
CAS No. 604769-01-9
Formula C19H19N5O4S
M. Wt 413.45
Purity >98%
Synonyms JNJ-16241199, JNJ16241199, JNJ 16241199
SMILES C1CN(CCN1C2=NC=C(C=N2)C(=O)NO)S(=O)(=O)C3=CC4=CC=CC=C4C=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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