Reparixin

Catalog No.: A12383

CXCL8/CXCR1/2 Inhibitor

Reparixin

Reparixin Chemical Structure

CAS NO. 266359-83-5

Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).

Availability: In stock

Package Price Qty
5 mg
$135.00
10 mg
$230.00
25 mg
$405.00
100 mg
$2,295.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Naour AL, .et al. Tumor cells educate mesenchymal stromal cells to release chemoprotective and immunomodulatory factors, J Mol Cell Biol, 2019, Sep 3 PMID: 31504643
  • Wigenstam E, .et al. N-acetyl cysteine improves the effects of corticosteroids in a mouse model of chlorine-induced acute lung injury, Toxicology, 2015, Feb 3;328:40-7 PMID: 25497111

Biological Activity

Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).
In vitro DMSO 52 mg/mL (183.49 mM)
Water Insoluble
Ethanol 52 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.29 mL 176.44 mL 352.87 mL
0.5 mM 7.06 mL 35.29 mL 70.57 mL
1 mM 3.53 mL 17.64 mL 35.29 mL
5 mM 0.71 mL 3.53 mL 7.06 mL

*The above data is based on the productmolecular weight 283.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12383
Actions Inhibitor
CAS No. 266359-83-5
Formula C14H21NO3S
M. Wt 283.39
Purity >98%
Synonyms DF 1681Y; Repertaxin
SMILES C[[email protected]](C1=CC=C(C=C1)CC(C)C)C(=O)NS(=O)(=O)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Reparixin | Reparixin Supplier | purchase | cost | manufacturer | order | distributor | buy 266359-83-5| 266359-83-5 Supplier | purchase 266359-83-5 | 266359-83-5 cost | 266359-83-5 manufacturer | order 266359-83-5 | 266359-83-5 distributor
Rewards