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CXCL8/CXCR1/2 Inhibitor

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Catalog No. A12383

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Reparixin 5mg A12383-5

Regular Price: CA$234.00

Special Price: CA$210.60

Reparixin 10mg A12383-10

Regular Price: CA$390.00

Special Price: CA$351.00

Reparixin 25mg A12383-25

Regular Price: CA$884.00

Special Price: CA$795.60

Reparixin 100mg A12383-100

Regular Price: CA$1,144.00

Special Price: CA$1,029.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).


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Publications citing Adooq Products
Reparixin Citations (1)
  • Wigenstam E, .et al. N-acetyl cysteine improves the effects of corticosteroids in a mouse model of chlorine-induced acute lung injury, Toxicology, 2015, Feb 3;328:40-7 PMID: 25497111

Chemical Information

Catalog Num A12383
Actions Inhibitor
M. Wt 283.39
Formula C14H21NO3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 266359-83-5
Synonyms DF 1681Y; Repertaxin
SMILES C[[email protected]](C1=CC=C(C=C1)CC(C)C)C(=O)NS(=O)(=O)C
Chemical Name (R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propanamide

Biological Activity

Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.29 mL 176.44 mL 352.87mL
0.5 mM 7.06 mL 35.29 mL 70.57 mL
1 mM 3.53 mL 17.64 mL 35.29 mL
5 mM 0.71 mL 3.53 mL 7.06 mL

*The above data is based on the productmolecular weight 283.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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