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- Naour AL, .et al. Tumor cells educate mesenchymal stromal cells to release chemoprotective and immunomodulatory factors, J Mol Cell Biol, 2019, Sep 3 PMID: 31504643
- Wigenstam E, .et al. N-acetyl cysteine improves the effects of corticosteroids in a mouse model of chlorine-induced acute lung injury, Toxicology, 2015, Feb 3;328:40-7 PMID: 25497111
Biological Activity
Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).
| In vitro | DMSO | 52 mg/mL (183.49 mM) | |
| Water | Insoluble | ||
| Ethanol | 52 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.29 mL | 176.44 mL | 352.87 mL |
| 0.5 mM | 7.06 mL | 35.29 mL | 70.57 mL |
| 1 mM | 3.53 mL | 17.64 mL | 35.29 mL |
| 5 mM | 0.71 mL | 3.53 mL | 7.06 mL |
*The above data is based on the productmolecular weight 283.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12383 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 266359-83-5 |
| Formula | C14H21NO3S |
| M. Wt | 283.39 |
| Purity | >98% |
| Synonyms | DF 1681Y; Repertaxin |
| SMILES | C[[email protected]](C1=CC=C(C=C1)CC(C)C)C(=O)NS(=O)(=O)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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