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RepSox (SJN 2511)


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Catalog No. A11762

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
RepSox (SJN 2511) 10mg A11762-10

Regular Price: $90.00

Special Price: $81.00

RepSox (SJN 2511) 25mg A11762-25

Regular Price: $200.00

Special Price: $180.00

RepSox (SJN 2511) 50mg A11762-50

Regular Price: $350.00

Special Price: $315.00

RepSox (SJN 2511) 100mg A11762-100

Regular Price: $600.00

Special Price: $540.00

RepSox (SJN 2511) 10mM * 1mL in DMSO A11762-10mM-D

Regular Price: $65.00

Special Price: $58.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

RepSox (SJN 2511) is a selective inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively).

RepSox (SJN 2511)

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Chemical Information

Catalog Num A11762
Actions N/A
M. Wt 287.32
Formula C17H13N5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 446859-33-2
Synonyms E-616452, SJN 2511, ALK 5 inhibitor

Biological Activity

RepSox (SJN 2511) is a selective inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively).
TGFβR1(ALK5) (Cell-free assay)
4 nM


Solubility (25°C)* In vitro DMSO 57 mg/mL (198.38 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.8 mL 174.02 mL 348.04mL
0.5 mM 6.96 mL 34.8 mL 69.61 mL
1 mM 3.48 mL 17.4 mL 34.8 mL
5 mM 0.7 mL 3.48 mL 6.96 mL

*The above data is based on the productmolecular weight 287.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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