RepSox (SJN 2511)

RepSox (SJN 2511) is a selective inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively).
Grouped product items
Product Name Price Stock Qty
RepSox (SJN 2511) 10mg
$90.00
In stock
RepSox (SJN 2511) 25mg
$200.00
In stock
RepSox (SJN 2511) 50mg
$350.00
In stock
RepSox (SJN 2511) 100mg
$600.00
In stock
RepSox (SJN 2511) 10mM * 1mL in DMSO
$65.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's RepSox (SJN 2511) has been cited by 2 publications
  • Wojciech J Szlachcic, .et al. , iScience, 2022, Jul 15;25(7) PMID: 35756892
  • Xu H, .et al. , Cancer Lett, 2020, Mar 1;472:151-164 PMID: 31846689
  • Biological Activity
    Discription RepSox (SJN 2511) is a selective inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively).
    Targets
    Target Value
    Product Information
    Catalog Num A11762
    Formula C17H13N5
    Molecular Weight 287.32
    CAS Number 446859-33-2
    SMILES CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4
    Synonyms E-616452, SJN 2511, ALK 5 inhibitor
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 49 mg/mL (170.54 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 34.8 mL 174.02 mL 348.04 mL
    0.5 mM 6.96 mL 34.8 mL 69.61 mL
    1 mM 3.48 mL 17.4 mL 34.8 mL
    5 mM 0.7 mL 3.48 mL 6.96 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy RepSox (SJN 2511) | RepSox (SJN 2511) Supplier | purchase RepSox (SJN 2511) | RepSox (SJN 2511) cost | RepSox (SJN 2511) manufacturer | order RepSox (SJN 2511) | RepSox (SJN 2511) distributor | buy 446859-33-2 | 446859-33-2 Supplier | purchase 446859-33-2 | 446859-33-2 cost | 446859-33-2 manufacturer | order 446859-33-2 | 446859-33-2 distributor