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RK-286D

Catalog No.: A27510
Antibiotic, PKC Inhibitor
RK-286D is a potent antibiotic and selective protein kinase C (PKC) inhibitor that exhibits significant antimicrobial properties. This compound effectively inhibits bleb formation induced by phorbol 12,13-dibutyrate (PDBu) and demonstrates notable activity in vitro against PKC. RK-286D is suitable for research applications exploring microbial resistance and PKC-related cellular signaling pathways.
RK-286D 140429-37-4 Antibiotic, PKC Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRK-286D is a potent antibiotic and selective protein kinase C (PKC) inhibitor that exhibits significant antimicrobial properties. This compound effectively inhibits bleb formation induced by phorbol 12,13-dibutyrate (PDBu) and demonstrates notable activity in vitro against PKC. RK-286D is suitable for research applications exploring microbial resistance and PKC-related cellular signaling pathways.
Product Information
Catalog NumA27510
FormulaC26H23N3O4
Molecular Weight441.48
CAS Number140429-37-4
SMILESO=C1C2=C3C(N([C@@H]4C[C@@H]([C@@H]([C@H](O4)C)O)O)C5=CC=CC=C53)=C6C(C7=CC=CC=C7N6)=C2CN1
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Microbiology > Antifection > Antibiotic