ROCK-IN-10 is a highly selective inhibitor of Rho-associated protein kinases (ROCK1 and ROCK2), exhibiting IC50 values of 6 nM and 4 nM, respectively. This compound demonstrates over 100-fold selectivity for ROCK over other kinases, making it an invaluable tool for research applications related to cellular signaling, cytoskeletal dynamics, and the study of various pathological conditions, including cancer and cardiovascular diseases. Researchers can utilize ROCK-IN-10 to investigate the role of ROCK in cellular processes and to explore potential therapeutic strategies targeting these kinases.
ROCK-IN-10 is a highly selective inhibitor of Rho-associated protein kinases (ROCK1 and ROCK2), exhibiting IC50 values of 6 nM and 4 nM, respectively. This compound demonstrates over 100-fold selectivity for ROCK over other kinases, making it an invaluable tool for research applications related to cellular signaling, cytoskeletal dynamics, and the study of various pathological conditions, including cancer and cardiovascular diseases. Researchers can utilize ROCK-IN-10 to investigate the role of ROCK in cellular processes and to explore potential therapeutic strategies targeting these kinases.
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