Rubiginone D2 is an antibiotic known for its antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, and Escherichia coli. In addition to its antibacterial properties, Rubiginone D2 demonstrates significant antitumor efficacy, inhibiting the proliferation of various cancer cell lines, including HM02, Kato III, HepG2, and MCF7, with GI50 values of 0.1, 0.7, less than 0.1, and 7.5 μM, respectively. This compound is valuable for research on antibiotic resistance and cancer therapeutics.
Rubiginone D2 is an antibiotic known for its antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, and Escherichia coli. In addition to its antibacterial properties, Rubiginone D2 demonstrates significant antitumor efficacy, inhibiting the proliferation of various cancer cell lines, including HM02, Kato III, HepG2, and MCF7, with GI50 values of 0.1, 0.7, less than 0.1, and 7.5 μM, respectively. This compound is valuable for research on antibiotic resistance and cancer therapeutics.
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