(S,R,S)-Ahpc-PEG6-azide

Catalog No.: A84430
PROTAC Linker
(S,R,S)-Ahpc-PEG6-azide is a click chemistry PROTAC linker that integrates an E3 ligase ligand and a PEG6 arm, facilitating the advancement of PROTAC research and discovery. The hydrophilic PEG spacer enhances solubility in aqueous environments, making it suitable for various biological applications. The presence of the azide functionality allows for efficient click chemistry reactions with alkyne, DBCO, or BCN molecules, thereby enabling versatile conjugation strategies in drug development.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S,R,S)-Ahpc-PEG6-azide is a click chemistry PROTAC linker that integrates an E3 ligase ligand and a PEG6 arm, facilitating the advancement of PROTAC research and discovery. The hydrophilic PEG spacer enhances solubility in aqueous environments, making it suitable for various biological applications. The presence of the azide functionality allows for efficient click chemistry reactions with alkyne, DBCO, or BCN molecules, thereby enabling versatile conjugation strategies in drug development.
Product Information
Catalog NumA84430
FormulaC37H57N7O10S
Molecular Weight791.95
CAS Number2767219-19-0
SMILES[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCC(N[C@@H](C(C)(C)C)C(N1[C@H](C[C@@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O
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