Santacruzamate A (CAY10683) is a potent and selective HDAC inhibitor with IC50 of 119 pM for HDAC2, >3600-fold selectivity over other HDACs.
Targets
Target
Value
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A14236
Formula
C15H22N2O3
Molecular Weight
278.35
CAS Number
1477949-42-0
SMILES
CCOC(=O)NCCCC(=O)NCCC1=CC=CC=C1
Synonyms
CAY10683
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
47 mg/mL (168.85 mM)
Water
Insoluble
Ethanol
47 mg/mL (168.85 mM)
In vivo
5%DMSO+30%PEG300+5%TW80+H2O
9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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