Saquayamycin D is an antibiotic derived from the culture broth of Streptomyces nodosus. This compound demonstrates significant antibacterial activity against a range of gram-positive bacteria, exhibiting a minimum inhibitory concentration (MIC) of 12.5-50 μg/mL. Additionally, Saquayamycin D effectively inhibits the proliferation of both Doxorubicin-sensitive P388/S and Doxorubicin-resistant P388/ADR cell lines, with an IC50 of 0.15 μg/mL, making it valuable for cancer research applications.
Saquayamycin D is an antibiotic derived from the culture broth of Streptomyces nodosus. This compound demonstrates significant antibacterial activity against a range of gram-positive bacteria, exhibiting a minimum inhibitory concentration (MIC) of 12.5-50 μg/mL. Additionally, Saquayamycin D effectively inhibits the proliferation of both Doxorubicin-sensitive P388/S and Doxorubicin-resistant P388/ADR cell lines, with an IC50 of 0.15 μg/mL, making it valuable for cancer research applications.
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