SARS-CoV-IN-3 is a potent inhibitor of SARS-CoV replication, demonstrating anti-Coronavirus activity with an EC50 value of 3.6 μM in Vero cells. Additionally, it exhibits antimalarial properties against P. falciparum strains 3D7 and W2, with IC50 values of 11.7 nM and 20.4 nM, respectively. SARS-CoV-IN-3 also effectively mitigates HIV-1-induced cytopathic effects, yielding an EC50 of 10 μM in MT-4 cells. This compound is valuable for research in virology and parasitology.
SARS-CoV-IN-3 is a potent inhibitor of SARS-CoV replication, demonstrating anti-Coronavirus activity with an EC50 value of 3.6 μM in Vero cells. Additionally, it exhibits antimalarial properties against P. falciparum strains 3D7 and W2, with IC50 values of 11.7 nM and 20.4 nM, respectively. SARS-CoV-IN-3 also effectively mitigates HIV-1-induced cytopathic effects, yielding an EC50 of 10 μM in MT-4 cells. This compound is valuable for research in virology and parasitology.
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