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Biological Activity
SBC-115076 is an anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compounds, for the treatment and/or prevention of cardiovascular diseases.
Targets
| PCSK9 | ||||
| In vitro (25°C) | DMSO | 28 mg/mL (53.06 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+45% PEG 300+ddH2O | 6 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.95 mL | 94.77 mL | 189.53 mL |
| 0.5 mM | 3.79 mL | 18.95 mL | 37.91 mL |
| 1 mM | 1.9 mL | 9.48 mL | 18.95 mL |
| 5 mM | 0.38 mL | 1.9 mL | 3.79 mL |
*The above data is based on the productmolecular weight 527.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15769 |
|---|---|
| Actions | Antagonist |
| CAS No. | 489415-96-5 |
| Formula | C31H33N3O5 |
| M. Wt | 527.61 |
| Purity | >98% |
| Synonyms | SBC 115076, SBC115076 |
| SMILES | CC1=C(C=CC(=C1)C(=C2C(N(C(=O)C2=O)CCCN3CCOCC3)C4=CC=NC=C4)O)OCC5=CC=CC=C5 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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