Secnidazole hemihydrate

Catalog No.: A46699
Antibiotic
Secnidazole hemihydrate is an orally active azole antibiotic that targets bacterial virulence through its amelioration of Serratia marcescens. This compound acts as an analog of acylhomoserine lactones, effectively inhibiting quorum sensing and reducing the pathogenesis of Pseudomonas aeruginosa. Secnidazole hemihydrate demonstrates antimicrobial activity against a range of anaerobic Gram-negative and Gram-positive bacteria in vitro. Its versatile applications in research include the study of diseases such as amoebiasis, giardiasis, and bacterial vaginitis.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSecnidazole hemihydrate is an orally active azole antibiotic that targets bacterial virulence through its amelioration of Serratia marcescens. This compound acts as an analog of acylhomoserine lactones, effectively inhibiting quorum sensing and reducing the pathogenesis of Pseudomonas aeruginosa. Secnidazole hemihydrate demonstrates antimicrobial activity against a range of anaerobic Gram-negative and Gram-positive bacteria in vitro. Its versatile applications in research include the study of diseases such as amoebiasis, giardiasis, and bacterial vaginitis.
Product Information
Catalog NumA46699
FormulaC7H13N3O4
Molecular Weight194.19
CAS Number227622-73-3
SMILESOC(C)CN1C([N+]([O-])=O)=CN=C1C.[1/2].O
SynonymsRP-14539 hemihydrate; PM-185184 hemihydrate
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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