Biological Activity
SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to the RGD-containing tetra-peptide SF1174 with potential antineoplastic and antiangiogenic activities.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 11.73 mL | 58.63 mL | 117.26 mL |
0.5 mM | 2.35 mL | 11.73 mL | 23.45 mL |
1 mM | 1.17 mL | 5.86 mL | 11.73 mL |
5 mM | 0.23 mL | 1.17 mL | 2.35 mL |
*The above data is based on the productmolecular weight 852.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A12704 |
---|---|
Actions | Inhibitor |
CAS No. | 936487-67-1 |
Formula | C39H48N8O14 |
M. Wt | 852.84 |
Purity | >98% |
Synonyms | SF 1126, SF-1126 |
SMILES | C1COCC[N+]1(COC(=O)CCC(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)[O-])C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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