SF1126

Catalog No.: A12704

Pan PI3K inhibitor

SF1126

SF1126 Chemical Structure

CAS NO. 936487-67-1

SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to the RGD-containing tetra-peptide SF1174 with potential antineoplastic and antiangiogenic activities.

Availability: Out of stock

Package Price
5 mg
$350.00
10 mg
$650.00
25 mg
$1,200.00
50 mg
$2,000.00
Custom Size Get quote
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to the RGD-containing tetra-peptide SF1174 with potential antineoplastic and antiangiogenic activities.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.73 mL 58.63 mL 117.26 mL
0.5 mM 2.35 mL 11.73 mL 23.45 mL
1 mM 1.17 mL 5.86 mL 11.73 mL
5 mM 0.23 mL 1.17 mL 2.35 mL

*The above data is based on the productmolecular weight 852.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12704
Actions Inhibitor
CAS No. 936487-67-1
Formula C39H48N8O14
M. Wt 852.84
Solubility DMSO
Purity >98%
Synonyms SF 1126, SF-1126
SMILES C1COCC[N+]1(COC(=O)CCC(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)[O-])C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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