Sivopixant is a selective antagonist of the P2X3 receptor, exhibiting a potent inhibitory activity with an IC50 of 4.2 nM for P2X3 and 1100 nM for P2X2/3. This compound demonstrates significant analgesic properties, making it valuable for research focused on pain pathways and therapeutic applications in pain management. Sivopixant can be utilized in studies investigating the role of purinergic signaling in nociception and related disorders.
Sivopixant is a selective antagonist of the P2X3 receptor, exhibiting a potent inhibitory activity with an IC50 of 4.2 nM for P2X3 and 1100 nM for P2X2/3. This compound demonstrates significant analgesic properties, making it valuable for research focused on pain pathways and therapeutic applications in pain management. Sivopixant can be utilized in studies investigating the role of purinergic signaling in nociception and related disorders.
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