SKLB-23bb

Catalog No.: A18339
HDAC6 inhibitor
SKLB-23bb is a potent and selective inhibitor for HDAC6 with an IC50 of 17 nM and shows 25-fold and 200-fold selectivity relative to HDAC1 (IC50=422 nM) and HDAC8 (IC50=3398 nM), respectively.
Grouped product items
Product Name Price Stock Qty
SKLB-23bb 1mg
$120.00
In stock
SKLB-23bb 5mg
$350.00
In stock
SKLB-23bb 10mg
$520.00
In stock
SKLB-23bb 50mg
$1,680.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription SKLB-23bb is a potent and selective inhibitor for HDAC6 with an IC50 of 17 nM and shows 25-fold and 200-fold selectivity relative to HDAC1 (IC50=422 nM) and HDAC8 (IC50=3398 nM), respectively.
Product Information
Catalog Num A18339
Formula C21H24N4O4
Molecular Weight 396.447
CAS Number 1815580-06-3
SMILES O=C(NO)CCCOC1=CC(N(C)C2=C3C=CC=CC3=NC(C)=N2)=CC=C1OC
Synonyms SKLB 23bb, SKLB23bb
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 76 mg/mL (191.7 mM)
Water Insoluble
Ethanol 76 mg/mL (191.7 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.22 mL 126.12 mL 252.24 mL
0.5 mM 5.04 mL 25.22 mL 50.45 mL
1 mM 2.52 mL 12.61 mL 25.22 mL
5 mM 0.5 mL 2.52 mL 5.04 mL
Useful Calculator

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