United States
You have no items in your shopping cart.
Publications citing Adooq Products
SRT1720 HCl Citations (6)
- Jie Ren,et al. Melatonin prevents chronic intermittent hypoxia-induced injury by inducing sirtuin 1-mediated autophagy in steatotic liver of mice, Sleep Breath, 2018, Nov 8 30411173
- Rowlands BD,et al. Acetate metabolism does not reflect astrocytic activity, contributes directly to GABA synthesis, and is increased by silent information regulator 1 activation, J Neurochem, 2017, Mar;140(6):903-918 27925207
- Adam Khader,et al. SRT1720, a sirtuin 1 activator, attenuates organ injury and inflammation in sepsis, J Surg Res, 2017, Nov;219:288-295 29078895
- Adam Khader,et al. Sirtuin 1 Stimulation Attenuates Ischemic Liver Injury and Enhances Mitochondrial Recovery and Autophagy, Crit Care Med, 2016, Aug; 44(8): e651-e663 26963320
- Benjamin D. Rowlands,et al. Silent information regulator 1 modulator resveratrol increases brain lactate production and inhibits mitochondrial metabolism, whereas SRT1720 increases oxidative metabolism., J Neurosci Res., 2015, Jul;93(7):1147-56 25677687
- Khader A,et al. Sirtuin 1 activation stimulates mitochondrial biogenesis and attenuates renal injury after ischemia-reperfusion., Transplantation, 2014, 98(2):148-56 24918615
Chemical Information
| Catalog Num | A10862 |
|---|---|
| Actions | Activator |
| M. Wt | 506.0 |
| Formula | C25H23N7OS.HCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1001645-58-4 |
| Synonyms | SRT-1720 |
| SMILES code | C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl |
| Chemical Name | N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide |
Description |
SRT1720 is an inhibitor developed intended as a small-molecule activator of the sirtuin subtype SIRT1. | ||||||||||
Targets |
|
||||||||||
| Solubility (25°C) * | In vitro | DMSO | 38 mg/mL (75.09 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.76 mL | 98.81 mL | 197.63mL |
| 0.5 mM | 3.95 mL | 19.76 mL | 39.53 mL |
| 1 mM | 1.98 mL | 9.88 mL | 19.76 mL |
| 5 mM | 0.4 mL | 1.98 mL | 3.95 mL |
*The above data is based on the productmolecular weight 506.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Ordering online
To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.
To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.
When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards. We will then liaise with you or your purchasing department to confirm the order.
Found your products but not ready to order?
Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.
Ordering offline
You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order. Our contact details are:
- Tel: 866-930-6790
- Fax: 323-606-8156
- Email: [email protected]
We require the following information to process your order:
- The catalog number for each product.
- Your email address or fax number.
- Your name and telephone number.
- Shipping address and billing address.
- Purchase order numbers.
Similar product(s)
Special Price Starting at:
$71.00
Tenovin-1 is a small molecule activator of p53 transcriptional activity that protects against MDM2-mediated p53 degradation. ...
Special Price Starting at: $71.00
Special Price Starting at:
$280.00
N/A ...
Special Price Starting at: $280.00
Special Price Starting at:
$22.50
EX 527 is a potent and selective SIRT1 class III histone deacetylase enzyme inhibitor with IC50 of 38 nM in a cell-free assay. ...
Special Price Starting at: $22.50
Keywords:buy SRT1720 HCl | SRT1720 HCl Supplier | purchase SRT1720 HCl | SRT1720 HCl cost | SRT1720 HCl manufacturer | order SRT1720 HCl | SRT1720 HCl distributor | buy 1001645-58-4| 1001645-58-4 Supplier | purchase 1001645-58-4 | 1001645-58-4 cost | 1001645-58-4 manufacturer | order 1001645-58-4 | 1001645-58-4 distributor
We Using Safe Payments:
