SRT1720 HCl

Name: SRT1720 HCl
SKU: A10862

Catalog No.: A10862

SIRT1 Activator

Product Citations (6)

SRT1720 HCl Chemical Structure

CAS NO. 1001645-58-4

SRT1720 is an inhibitor developed intended as a small-molecule activator of the sirtuin subtype SIRT1.

Availability: In stock

Package	Price	Qty
5 mg	$90.00
10 mg	$160.00
50 mg	$450.00
200 mg	$1,200.00
10mM * 1mL in DMSO	$150.00

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

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Biological Activity

SRT1720 is an inhibitor developed intended as a small-molecule activator of the sirtuin subtype SIRT1.

Targets

SIRT1 (Cell-free assay)
0.16 μM(EC50)

Solubility *

In vitro (25°C)	DMSO	38 mg/mL (75.09 mM)
	Water	<1 mg/mL (<1 mM)
	Ethanol	<1 mg/mL (<1 mM)
In vivo	30% PEG400/0.5% Tween80/5% propylene glycol	30 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.76 mL	98.81 mL	197.63 mL
0.5 mM	3.95 mL	19.76 mL	39.53 mL
1 mM	1.98 mL	9.88 mL	19.76 mL
5 mM	0.4 mL	1.98 mL	3.95 mL

*The above data is based on the productmolecular weight 506.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A10862
Actions	Activator
M. Wt	506.0
Formula	C25H23N7OS.HCl
Solubility	DMSO
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1001645-58-4
Synonyms	SRT-1720
SMILES	C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl