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SRT1720 is an inhibitor developed intended as a small-molecule activator of the sirtuin subtype SIRT1.
Targets
| SIRT1 (Cell-free assay) | ||||
| 0.16 μM(EC50) |
| In vitro (25°C) | DMSO | 38 mg/mL (75.09 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.76 mL | 98.81 mL | 197.63 mL |
| 0.5 mM | 3.95 mL | 19.76 mL | 39.53 mL |
| 1 mM | 1.98 mL | 9.88 mL | 19.76 mL |
| 5 mM | 0.4 mL | 1.98 mL | 3.95 mL |
*The above data is based on the productmolecular weight 506.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A10862 |
|---|---|
| Actions | Activator |
| M. Wt | 506.0 |
| Formula | C25H23N7OS.HCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1001645-58-4 |
| Synonyms | SRT-1720 |
| SMILES | C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl |
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