STING agonist-46 is a potent STING agonist that activates the stimulator of interferon genes (STING) signaling pathway, leading to the phosphorylation of TBK1 and IRF3 as well as the secretion of key cytokines such as IFN-β and IP-10. By directly binding to STING, it enhances thermal stability and elicits significant anti-tumor effects in mouse models, including B16F10, CT26, and 4T1. This compound is suitable for research applications focused on cancer immunotherapy and the elucidation of STING-related immune responses.
STING agonist-46 is a potent STING agonist that activates the stimulator of interferon genes (STING) signaling pathway, leading to the phosphorylation of TBK1 and IRF3 as well as the secretion of key cytokines such as IFN-β and IP-10. By directly binding to STING, it enhances thermal stability and elicits significant anti-tumor effects in mouse models, including B16F10, CT26, and 4T1. This compound is suitable for research applications focused on cancer immunotherapy and the elucidation of STING-related immune responses.
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