STR-V-53

Catalog No.: A26488
HDAC Inhibitor
STR-V-53 is a histone deacetylase (HDAC) inhibitor with a low nanomolar IC50. By inhibiting HDAC activity, STR-V-53 increases histone acetylation, leading to altered gene expression. This compound exhibits significant anti-tumor properties, inhibiting proliferation and promoting apoptosis in cancer cells. It serves as a valuable research tool for studying epigenetic regulation and potential therapeutic strategies in oncology.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSTR-V-53 is a histone deacetylase (HDAC) inhibitor with a low nanomolar IC50. By inhibiting HDAC activity, STR-V-53 increases histone acetylation, leading to altered gene expression. This compound exhibits significant anti-tumor properties, inhibiting proliferation and promoting apoptosis in cancer cells. It serves as a valuable research tool for studying epigenetic regulation and potential therapeutic strategies in oncology.
Product Information
Catalog NumA26488
FormulaC21H30N4O8
Molecular Weight466.48
CAS Number2798954-66-0
SMILESOC[C@H]1O[C@H](OC2=CC=C(C3=CN(CCCCCCC(NO)=O)N=N3)C=C2)[C@H](O)[C@@H](O)[C@@H]1O
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