Sunitinib Malate

Catalog No.: A10880

Sunitinib Malate

Sunitinib Malate Chemical Structure

CAS NO. 341031-54-7

Sunitinib is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).

Availability: In stock

Package Price Qty
50 mg

Regular Price: $40.00

Special Price $32.00

100 mg

Regular Price: $65.00

Special Price $52.00

200 mg

Regular Price: $100.00

Special Price $80.00

500 mg

Regular Price: $200.00

Special Price $160.00

10mM * 1mL in DMSO
$63.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Sunitinib is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
Targets
Target Value
Kit
FLT3
PDGFRβIC50: 2nM
VEGFR2IC50: 80nM
FGFR1IC50: 2.9μM
EGFRIC50: >20μM
In vitro (25°C) DMSO 15 mg/mL (28.16 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC, pH3.5 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.78 mL 93.88 mL 187.76 mL
0.5 mM 3.76 mL 18.78 mL 37.55 mL
1 mM 1.88 mL 9.39 mL 18.78 mL
5 mM 0.38 mL 1.88 mL 3.76 mL

*The above data is based on the productmolecular weight 532.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10880
Actions No
M. Wt 532.6
Formula C22H27FN4O2.C4H6O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 341031-54-7
Synonyms SU-11248
SMILES CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\2/C3=C(C=CC(=C3)F)NC2=O)C.C([[email protected]@H](C(=O)O)O)C(=O)O

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