Sunitinib

Catalog No.: A17858

multi-targeted receptor tyrosine kinase inhibitor

Sunitinib

Sunitinib Chemical Structure

CAS NO. 557795-19-4

Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively.

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100 mg

Regular Price: $54.00

Special Price $43.20

500 mg

Regular Price: $162.00

Special Price $129.60

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Biological Activity

Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively.
In vitro (25°C) DMSO Warmed: 23 mg/mL (57.71 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 0.83 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.1 mL 125.48 mL 250.96 mL
0.5 mM 5.02 mL 25.1 mL 50.19 mL
1 mM 2.51 mL 12.55 mL 25.1 mL
5 mM 0.5 mL 2.51 mL 5.02 mL

*The above data is based on the productmolecular weight 398.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17858
Actions Inhibitor
CAS No. 557795-19-4
Formula C22H27FN4O2
M. Wt 398.47
Purity >98%
Synonyms SU 11248, SU11248, SU-11248
SMILES O=C(NCCN(CC)CC)C1=C(NC(/C=C2C(NC3=C\2C=C(C=C3)F)=O)=C1C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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