Sunitinib

Catalog No.: A17858
multi-targeted receptor tyrosine kinase inhibitor
Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively.
Grouped product items
Product Name Price Stock Qty
Sunitinib 100mg
$54.00
In stock
Sunitinib 500mg
$162.00
In stock
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Adooq Products cited in reputable paper
Adooq's Sunitinib has been cited by 1 publications
  • Wei Kang Cheng, .et al. , Microvasc Res, 2022, Feb 11;142:104341 PMID: 35157839
  • Biological Activity
    Discription Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A17858
    Formula C22H27FN4O2
    Molecular Weight 398.47
    CAS Number 557795-19-4
    SMILES O=C(NCCN(CC)CC)C1=C(NC(/C=C2C(NC3=C\2C=C(C=C3)F)=O)=C1C)C
    Synonyms SU 11248, SU11248, SU-11248
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 23 mg/mL (57.71 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+corn oil 0.83 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.1 mL 125.48 mL 250.96 mL
    0.5 mM 5.02 mL 25.1 mL 50.19 mL
    1 mM 2.51 mL 12.55 mL 25.1 mL
    5 mM 0.5 mL 2.51 mL 5.02 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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