Sunitinib
Important Notice: For research use only. We do not sell to patients.
Other Forms of Sunitinib
Not your Region? View all Distributors
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively. | ||
---|---|---|---|
Targets |
|
Catalog Num | A17858 |
---|---|
Formula | C22H27FN4O2 |
Molecular Weight | 398.47 |
CAS Number | 557795-19-4 |
SMILES | O=C(NCCN(CC)CC)C1=C(NC(/C=C2C(NC3=C\2C=C(C=C3)F)=O)=C1C)C |
Synonyms | SU 11248, SU11248, SU-11248 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 23 mg/mL (57.71 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+corn oil | 0.83 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.1 mL | 125.48 mL | 250.96 mL |
0.5 mM | 5.02 mL | 25.1 mL | 50.19 mL |
1 mM | 2.51 mL | 12.55 mL | 25.1 mL |
5 mM | 0.5 mL | 2.51 mL | 5.02 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2