TAN-420E (Dihydroherbimycin A) is an antibiotic derived from the fermentation of Streptomyces hygroscopicus. This compound demonstrates significant cytotoxicity against P-388 and KB cancer cell lines, highlighting its potential as an anti-cancer agent. In addition, TAN-420E effectively scavenges DPPH free radicals, with an IC50 value of 1.3 μM, indicating its potential antioxidant properties. Research applications include investigations into its antimicrobial and anticancer effects.
TAN-420E (Dihydroherbimycin A) is an antibiotic derived from the fermentation of Streptomyces hygroscopicus. This compound demonstrates significant cytotoxicity against P-388 and KB cancer cell lines, highlighting its potential as an anti-cancer agent. In addition, TAN-420E effectively scavenges DPPH free radicals, with an IC50 value of 1.3 μM, indicating its potential antioxidant properties. Research applications include investigations into its antimicrobial and anticancer effects.
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