TAPI-2

Catalog No.: A14009

TACE/MMP inhibitor

TAPI-2

TAPI-2 Chemical Structure

CAS NO. 187034-31-7

TAPI-2 is an inhibitor of TACE, ADAMs, ACE secretase, and other MMPs (metalloproteinases). TAPI-2 blocks release of DCC7, APP, TNFα, L-selectin, NOTCH, TGFα, IL-6R9, erbB2/HER2, and ACE. This inhibitor has been used in tissue culture.

Availability: In stock

Package Price Qty
2 mg
$180.00
5 mg
$400.00
10 mg
$750.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TAPI-2 is an inhibitor of TACE, ADAMs, ACE secretase, and other MMPs (metalloproteinases). TAPI-2 blocks release of DCC7, APP, TNFα, L-selectin, NOTCH, TGFα, IL-6R9, erbB2/HER2, and ACE. This inhibitor has been used in tissue culture.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.07 mL 120.33 mL 240.66 mL
0.5 mM 4.81 mL 24.07 mL 48.13 mL
1 mM 2.41 mL 12.03 mL 24.07 mL
5 mM 0.48 mL 2.41 mL 4.81 mL

*The above data is based on the productmolecular weight 415.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A14009
Actions Inhibitor
M. Wt 415.53
Formula C19H37N5O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 187034-31-7
Synonyms TNF Protease Inhibitor 2
SMILES C[[email protected]@H](C(=O)NCCN)NC(=O)[[email protected]](C(C)(C)C)NC(=O)C(CC(C)C)CC(=O)NO

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