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TCS PIM-1 1

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Pim-1 Kinase Inhibitor

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Catalog No. A15369

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
TCS PIM-1 1 10mg A15369-10

Regular Price: $110.00

Special Price: $99.00

TCS PIM-1 1 50mg A15369-50

Regular Price: $270.00

Special Price: $243.00

TCS PIM-1 1 100mg A15369-100

Regular Price: $500.00

Special Price: $450.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

TCS PIM-1 1 is a potent and selective ATP-competitive Pim-1 kianse inhibitor with IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2(IC50s >20,000 nM).

TCS PIM-1 1

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Chemical Information

Catalog Num A15369
Actions Inhibitor
M. Wt 367.2
Formula C18H11BrN2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 491871-58-0
Synonyms SC 204330, TCS PIM 1-1
SMILES C1=CC=C(C=C1)C2=C(C(=O)NC(=C2)C3=C(C=CC(=C3)Br)O)C#N

Biological Activity

Description
TCS PIM-1 1 is a potent and selective ATP-competitive Pim-1 kianse inhibitor with IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2(IC50s >20,000 nM).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.23 mL 136.17 mL 272.33mL
0.5 mM 5.45 mL 27.23 mL 54.47 mL
1 mM 2.72 mL 13.62 mL 27.23 mL
5 mM 0.54 mL 2.72 mL 5.45 mL

*The above data is based on the productmolecular weight 367.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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