TCS PIM-1 4a (SMI-4a)

Catalog No.: A11967

Pim inhibitor

TCS PIM-1 4a (SMI-4a) Chemical Structure

CAS NO. 438190-29-5

TCS PIM-1 4a is a selective and ATP-competitive Pim kinase inhibitor (IC50 values = 24 and 100 nM for Pim-1 and Pim-2, respectively).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $65.00

Special Price $52.00

25 mg

Regular Price: $150.00

Special Price $120.00

50 mg

Regular Price: $265.00

Special Price $212.00

10mM * 1mL in DMSO
$82.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TCS PIM-1 4a is a selective and ATP-competitive Pim kinase inhibitor (IC50 values = 24 and 100 nM for Pim-1 and Pim-2, respectively).
Targets
Pim1
17 nM
In vitro (25°C) DMSO 55 mg/mL (201.29 mM)
Water <1 mg/mL (<1 mM)
Ethanol 32 mg/mL (117.11 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.6 mL 183 mL 365.99 mL
0.5 mM 7.32 mL 36.6 mL 73.2 mL
1 mM 3.66 mL 18.3 mL 36.6 mL
5 mM 0.73 mL 3.66 mL 7.32 mL

*The above data is based on the productmolecular weight 273.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11967
Actions Inhibitor
M. Wt 273.23
Formula C11H6F3NO2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 438190-29-5
Synonyms 0
SMILES O=C(NC/1=O)SC1=C\C2=CC=CC(C(F)(F)F)=C2

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