TCS PIM-1 4a is a selective and ATP-competitive Pim kinase inhibitor (IC50 values = 24 and 100 nM for Pim-1 and Pim-2, respectively).
Targets
Target
Value
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A11967
Formula
C11H6F3NO2S
Molecular Weight
273.23
CAS Number
438190-29-5
SMILES
O=C(NC/1=O)SC1=C\C2=CC=CC(C(F)(F)F)=C2
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
47 mg/mL (172.01 mM)
Water
Insoluble
Ethanol
28 mg/mL (102.47 mM)
In vivo
30% PEG400+0.5% Tween80+5% propylene glycol
28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: