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Telavancin hydrochloride

Catalog No.: A46423
Antibiotic
Telavancin hydrochloride is an antibiotic that functions primarily by inhibiting cell wall synthesis and disrupting cell membrane barrier function. This semisynthetic derivative of vancomycin demonstrates significant antibacterial activity against antibiotic-resistant Staphylococcus aureus strains, including MRSA, VISA, and hVISA. Telavancin hydrochloride is particularly effective in treating complicated skin and skin structure infections (cSSSI) caused by gram-positive bacteria. This compound is valuable for research into antibiotic resistance and the development of novel antimicrobial therapies.
Telavancin hydrochloride 560130-42-9 Antibiotic
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1mg
$235.00
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5mg
$535.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTelavancin hydrochloride is an antibiotic that functions primarily by inhibiting cell wall synthesis and disrupting cell membrane barrier function. This semisynthetic derivative of vancomycin demonstrates significant antibacterial activity against antibiotic-resistant Staphylococcus aureus strains, including MRSA, VISA, and hVISA. Telavancin hydrochloride is particularly effective in treating complicated skin and skin structure infections (cSSSI) caused by gram-positive bacteria. This compound is valuable for research into antibiotic resistance and the development of novel antimicrobial therapies.
Product Information
Catalog NumA46423
FormulaC80H107Cl3N11O27P
Molecular Weight1792.10
CAS Number560130-42-9
SMILESClC1=CC([C@H]([C@H](C(N[C@H](C(N[C@@]2([H])C(N[C@]3([H])C4=CC=C(O)C(C5=C(O)C(CNCP(O)(O)=O)=C(O)C=C5[C@H](NC([C@](NC3=O)([H])[C@@H](C6=CC=C(O7)C(Cl)=C6)O)=O)C(O)=O)=C4)=O)=O)CC(N)=O)=O)NC([C@H](NC)CC(C)C)=O)O)=CC=C1OC8=C(C7=CC2=C8)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O[C@H]%10C[C@@](C)([C@@H]([C@@H](O%10)C)O)NCCNCCCCCCCCCC.Cl
SynonymsTD-6424 hydrochloride
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Microbiology > Antifection > Antibiotic