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Telomycin

Catalog No.: A46912
Antibiotic
Telomycin is a calcium-dependent antibiotic produced by Streptomyces species, with a primary mechanism of action that disrupts the growth of gram-positive bacteria. It demonstrates potent activity against multidrug-resistant (MDR) pathogens, making it a valuable tool for research in combating antibiotic resistance. Telomycin's unique properties position it as a critical compound for studies focused on bacterial infections and antibiotic development.
Telomycin 19246-24-3 Antibiotic
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Size Price Stock Qty
100µg
$145.00
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500µg
$440.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTelomycin is a calcium-dependent antibiotic produced by Streptomyces species, with a primary mechanism of action that disrupts the growth of gram-positive bacteria. It demonstrates potent activity against multidrug-resistant (MDR) pathogens, making it a valuable tool for research in combating antibiotic resistance. Telomycin's unique properties position it as a critical compound for studies focused on bacterial infections and antibiotic development.
Product Information
Catalog NumA46912
FormulaC59H77N13O19
Molecular Weight1272.32
CAS Number19246-24-3
Sequence{Bas}-Ser-Thr-Thr-Ala-Gly-{Pro(3S-OH)}-{Trp(α,β-Didehydro)}-{Trp(β-Me)}-{Leu(3S-OH)}-{Pro(3R-OH)} (lactone bridge: Thr3-Pro11)
Sequence shortening{Bas}-STTAG-{Pro(3S-OH)}-{Trp(α,β-Didehydro)}-{Trp(β-Me)}-{Leu(3S-OH)}-{Pro(3R-OH)} (lactone bridge: Thr3-Pro11)
SMILES[H][C@@]12[C@@H](O)CCN1C(=O)CNC(=O)[C@H](C)NC(=O)[C@@]([H])(NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)C[C@H](N)C(O)=O)[C@@H](C)OC(=O)[C@]1([H])[C@H](O)CCN1C(=O)[C@@]([H])(NC(=O)[C@@H](NC(=O)C(NC2=O)=Cc1c[nH]c2ccccc12)[C@@H](C)c1c[nH]c2ccccc12)[C@@H](O)C(C)C)[C@H](C)O |w:66.69|
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Microbiology > Antifection > Antibiotic