Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium is a potent HIV inhibitor that demonstrates significantly prolonged half-life values compared to tenofovir in human liver microsomes. This compound exhibits robust anti-HIV activity in vitro and shows enhanced pharmacokinetic properties in vivo. Additionally, it serves as a click chemistry reagent featuring an alkyne group, which allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating various research applications in medicinal chemistry and drug development.
Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium is a potent HIV inhibitor that demonstrates significantly prolonged half-life values compared to tenofovir in human liver microsomes. This compound exhibits robust anti-HIV activity in vitro and shows enhanced pharmacokinetic properties in vivo. Additionally, it serves as a click chemistry reagent featuring an alkyne group, which allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating various research applications in medicinal chemistry and drug development.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
