Thalidomide

Catalog No.: A10924

E3 ubiquitin ligase inhibitor

Thalidomide

Thalidomide Chemical Structure

CAS NO. 50-35-1

Thalidomide can directly inhibit angiogenesis induced by bFGF or VEGF in vivo.

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200 mg
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500 mg
$120.00
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Warning WARNING: Attention California Residents: This product can expose you to chemicals including Thalidomide , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Thalidomide can directly inhibit angiogenesis induced by bFGF or VEGF in vivo.
In vitro (25°C) DMSO 48 mg/mL (185.87 mM)
Water Insoluble
Ethanol 2 mg/mL (7.74 mM)
In vivo 5% DMSO+30% PEG 300+1% Tween 80+ddH2O (suspension) 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.73 mL 193.63 mL 387.25 mL
0.5 mM 7.75 mL 38.73 mL 77.45 mL
1 mM 3.87 mL 19.36 mL 38.73 mL
5 mM 0.77 mL 3.87 mL 7.75 mL

*The above data is based on the productmolecular weight 258.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10924
Actions Inhibitor
CAS No. 50-35-1
Formula C13H10N2O4
M. Wt 258.23
Purity >98%
SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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