Tkip

Name: Tkip
Brand: Adooq Bioscience
SKU: A33441
Rating: 5 (288 reviews)

Catalog No.: A33441

JAK2 Inhibitor

Tkip is a selective inhibitor of JAK2, targeting the JAK2 autophosphorylation site. It effectively inhibits JAK2 autophosphorylation and the phosphorylation of the IFN-γ receptor subunit IFNGR-1, thereby reducing the antiviral effects of IFN-γ and downregulating MHC Class I molecule expression. Tkip is a valuable tool for investigating the IFN-γ signaling pathway and its implications in various biological processes.

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Grouped product items
Size	Price	Stock
1mg	$40.00	In stock
5mg	$125.00	In stock
10mg	$200.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description

Product Information

Catalog Num	A33441
Formula	C93H118N16O14
Molecular Weight	1684.03
CAS Number	716361-65-8
Sequence	Trp-Leu-Val-Phe-Phe-Val-Ile-Phe-Tyr-Phe-Phe-Arg
Sequence shortening	WLVFFVIFYFFR
SMILES	C([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)=O)=O)=O)=O)[C@H](CC)C)=O)C(C)C)=O)=O)=O)[C@H](C)C)=O)CC(C)C)=O)N)C=7C=8C(NC7)=CC=CC8

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