TP-3654

Catalog No.: A20584
Pim kinase inhibitor
TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively.
Grouped product items
Product Name Price Stock Qty
TP-3654 5mg
$54.00
In stock
TP-3654 10mg
$93.00
In stock
TP-3654 50mg
$276.00
In stock
TP-3654 100mg
$552.00
In stock
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Biological Activity
Discription TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively.
Product Information
Catalog Num A20584
Formula C22H25F3N4O
Molecular Weight 418.46
CAS Number 1361951-15-6
SMILES OC(C)(C)[C@H]1CC[C@H](NC2=NN3C(C=C2)=NC=C3C4=CC=CC(C(F)(F)F)=C4)CC1
Synonyms TP3654, TP 3654
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 71 mg/mL (169.66 mM)
Water Insoluble
Ethanol 5 mg/mL (11.94 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.9 mL 119.49 mL 238.97 mL
0.5 mM 4.78 mL 23.9 mL 47.79 mL
1 mM 2.39 mL 11.95 mL 23.9 mL
5 mM 0.48 mL 2.39 mL 4.78 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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